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High blood pressure—a risk factor for heart attacks, heart failure and stroke—is 40 percent more common among African-Americans than in other American ethnic groups.
In a new BWH study in partnership with the Dana-Farber Cancer Institute and Massachusetts General Hospital, researchers found that vitamin D supplementation may help African-Americans lower their blood pressure.
“This study may explain and help treat an important public health disparity,” said the study’s lead author, John Forman, MD, of BWH’s Renal Division and Kidney Clinical Research Institute.
To conduct the study, 250 African-American adult voluntary research participants were divided into four groups. Three of the groups received a three-month regimen of daily vitamin D supplementation at various doses ranging between 1,000 and 4,000 units. The fourth group received a placebo.
Participants in the placebo group saw their systolic blood pressure rise, but participants in the supplementation groups had their systolic blood pressure decrease by one to four points, with those who received the highest dose benefiting the most. Systolic blood pressure is the top number in a blood pressure reading, measuring the pressure in the arteries when the heart beats.
“The gains were modest, but significant,” said Forman. “If further research supports our finding, widespread use of vitamin D supplementation in African-Americans could have significant public health benefits.”