Robert C . Green, MD, MPH
Selected Publications:
Diagnostic accuracy statistics for seven Neuropsychological Assessment Battery (NAB) test variables in the diagnosis of Alzheimer’s disease. Gavett BE, Lou KR, Daneshvar DH, Green RC, Jefferson AL, Stern RA, Applied Neuropsychology, in press. PubMed Link
Effects of FDA approved medications for Alzheimer’s disease on clinical progression. Mielke MM, Leoutsakos J-M, Cocoran CD, Green RC, Norton MC, Welsh-Bohmer KA, Tschanz JT, Lyketsos CG, Alzheimer’s & Dementia, in press.
Genetic variants at multiple loci influence Alzheimer disease in African Americans. Logue M, Schu MC, Vardarajan BN, Buros JL, Green RC, Griffith P, Akomolafe A, Go Rodney, Obisesan T, Cupples LA, Lunetta K, Fallin DM, Baldwin C, Archives of Neurology, in press.
Diagnosis and treatment of Alzheimer’s disease. Mandell A, Nair A, Green RC, in Kowell N, Budson A (eds), Alzheimer’s Disease and Other Dementia, Blackwell Publishing, in press.
Differences between African American and white research volunteers in their attitudes, beliefs and knowledge regarding genetic testing for Alzheimer’s disease. Akinleye D, Roberts JS, Royal CDM, Linnenbringer E, Obisesan T, Gasaye, G-A, Green RC, Journal of Genetic Counseling, epub ahead of print. PubMed Link
Using Alzheimer’s disease as a model for genetic risk disclosure: Implications for personal genomics. Roberts JS, Christensen KD, Green RC, Clinical Genetics, epub ahead of print. PubMed Link
Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Farrer LA, Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Neurobiology of Aging, in press. PubMed Link
The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer’s disease. Ready RE, Carvalho JO, Green RC, Gavett BE, Stern RA, International Psychogeriatrics, 23:887-898, 2011. PubMed Link
Progression of cognitive, functional and neuropsychiatric symptom domains in a population cohort with Alzheimer’s dementia: the cache county dementia progression study. Tschanz JT, Corcoran CD, Schwartz S, Treiber K, Green RC, Norton MC, Mielke MM, Piercy K, Steinberg M, Rabins PV, Leoutsakos JM, Welsh-Bohmer KA, Breitner JCS, Lyketsos CG, Journal of American Geriatric Psychiatry, 19: 532-542, 2011. PubMed Link
Changes to perceptions of the pros and cons of genetic susceptibility testing after POE genotyping for Alzheimer disease risk. Christensen K, Roberts JS, Uhlmann WR, Green RC, Genetics in Medicine, 13: 409-414, 2011.
Common variants in MS4A4/MS4A6, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease. Naj AC, Jun G, Beecham GW, Wang L-S, Narayan B, Green RC, Pericak-Vance MA, Farrer LA, Schellenberg GD, Nature Genetics, 43:436-441, 2011. PMC3090745.
Extended results of the Alzheimer’s disease anti-inflammatory prevention trial (ADAPT). Breitner JC, Baker LD, Montine TJ, Meinert CL, Lyketsos CG, Ashe KH, Brandt J, Craft S, Evans DE, Green RC, Ismail MS, Martin BK, Mullan MJ Sabbagh M, Tariot P, for the ADAPT Research Group, Alzheimer’s & Dementia, 7:402-411, 2011. PubMed Link
The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype. Johnson SC, Rue AL, Hermann BP, Xu G, Koscik RL, Jonaitis EM, Bendlin BB, Roses AD, Saunders AM, Lutz MW, Asthana S, Green RC, Sager MA, Alzheimer’s & Dementia, 7:456-465, 2011. PubMed Link
Hippocampal sclerosis in advanced age: Clinical and pathological features. Nelson PJ, Schmitt FA, Lin Y, Abner EL, Jicha GA, Patel E, Thomason PC, Netler JH, Smith CD, Santacurz KS, Sonnen JA, Poon LW, Gearing M, Green RC, Woodard JL, Van Eldik LJ, Kryscio RJ, Brain, 134: 1506-1518, 2011. PubMed Link
Progression of cognitive, functional, and neuropsychiatric symptom domains in a population cohort with Alzheimer dementia: the cache county dementia progression study. Tschanz JT, Corcoran CD, Schwartz S, Treiber K, Green RC, Norton MC, Mielke MM, Piercy K, Steinberg M, Rabins PV, Leoutsakos JM, Welsh-Bohmer KA, Breitner JCS, Lyketsos CG, Journal of American Geriatric Psychiatry, 19:532-542, 2011. PMC3101372. PubMed Link
Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families . Cuenco KT, Friedland R, Baldwin CT, Guo J, Vardarajan B, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA, Neurobiology of Aging, 32:249-256, 2011. PubMed Link
The role of disease perceptions and results sharing on psychological adaptation in genetic susceptibility testing: The REVEAL Study . Ashida S, Koehly L, Roberts JS, Chen C, Hiraki S, Green RC, European Journal of Human Genetics, epub: 1-6, 2010. PubMed Link
The authors reply to letter to the editor: Disclosure of the Genetic Risk of Alzheimer’s Disease. Roberts JS, Cupples LA, Green RC, New England Journal of Medicine, 362:182, 2010. NEJM Link
Head circumference, atrophy and cognition: Implications for brain reserve in Alzheimer disease. Pernecsky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green R DeCarli C, Farrer LA, Kurz A, for the MIRAGE Study Group, Neurology, 75:137-142, 2010. PubMed Link
Clock Drawing Test ratings by dementia specialists – Inter-rater reliability and diagnostic accuracy . Nair AK, Gavett BE, Damman M, Dekker W, Green RC, Auerbach S, Mandel A, Steinberg E, Hubbard EJ, Jefferson AJ, Stern RA, Journal of Neuropsychiatry and Clinical Neurosciences, 22:85-92, 2010. PubMed Link
Interaction between vascular factors and the APOE E4 allele in predicting rate of progression in Alzheimer’s disease. Mielke MM, Leoutsakos J-M, Tschanz JT, Green RC, Tripodis Y, Cocoran CD, Norton MC, Lyketsos CG, Journal of Alzheimer’s Disease, epub ahead of print. PubMed Link
Willingness to pay for genetic testing for Alzheimer’s disease: A measure of personal utility. Kopits IM, Chen C, Roberts JS, Uhlmann W, Green RC, Genetic Testing and Molecular Biomarkers, epub ahead of print. PubMed Link
Mild Cognitive Impairment in clinical care: A survey of neurologists’ attitudes and practices. Roberts JS, Karlawish J, Uhlmann W, Petersen R, Green RC, Neurology, 75(5): 425-431, 2010. PubMed Link
Predicting cognitive decline and conversion to Alzheimer’s disease in older adults using the NAB List Learning test. Gavett BE, Ozonoff A, Doktor V, Palmisano J, Nair AK, Green RC, Jefferson AL, Stern RA, Journal of the International Neuropsychological Society, 16(4):651-660, 2010. PubMed Link
ADNI biomarkers as quantitative phenotypes: Genetics core aims, progress and plans. Saykin AJ, Shen L, Foroud TM, Potkin SG, Shanker S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craid DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, Bertram L, Jack CR, Weiner MW, and the Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s and Dementia, 6:265-273, 2010. PubMed Link
The Alzheimer’s Disease Neuroimaging Initiative: Progress report and future plans. Weiner MW, Aisen PS, Jack CR, Jagust WJ, Trojanowski JQ, Shaw L, Saykin AJ, Morris JC, Caims N, Becket LA, Toga A, Green RC, Walter S, Soares H, Snyder P, Siemers E, Potter W, Cole PE, Schmidt M, and the Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s & Dementia, 6:202-211, 2010. PubMed Link
The Alzheimer’s Disease Neuroimaging Initiative-Progress report and future plans. Saykin AJ, Shen L, Foroud TM, Potkin SG, Shanker S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, Bertram L, Jack CR, Weiner MW, and the Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s & Dementia, 6:265-273, 2010.
“I know what you told me, but this is what I think”: Perceived risk of Alzheimer’s disease among individuals who accurately recall their genetics-based risk estimate. Linnenbringer E, Roberts JS, Hiraki S, Cupples LA, Green RC, Genetics in Medicine, 12(4):219-227, 2010. PubMed Link
Effect of Alzheimer disease genetic risk disclosure on dietary supplement use. Vernarelli JA, Roberts JS, Chen CA, Cupples LA, Green RC The American Journal of Clinical Nutrition, 91:1402-1407, 2010. PubMed Link
Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer’s disease. Eggermont LH, Gavett BE, Volkers KM, Blankevoort CG, Scherder EJ, Jefferspn AL, Steinberg E, Nair A, Green RC, Stern R, Archives of Physical Medicine and Rehabilitation, 91:584-588, 2010. PubMed Link
Genetic testing For Alzheimer’s in long-term care insurance. Taylor DH, Cood-Deegan R, Hiraki S, Roberts JS, Blazer DG, Green RC, Health Affairs, 29:102-108, 2010. PubMed Link
Effect of Tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer’s Disease. A randomized controlled trial. Green RC, Schneider LS, Amato DA, Beelen AP, Wilcock G, Swabb EA, Zavitz KH, JAMA, 302:2557-2565, 2009. PubMed Link
Correspondence of Perceptions about Centenarians’ Mental Health. MacDonald M, Martin P, Margrett J, Poon LW, for the Georgia Centenarian Study*, Aging and Mental Health, 13(6):827-837, 2009. (*member of the investigative team cited in the appendix of the manuscript). PubMed Link
Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer’s disease: The MIRAGE Study. Perneczky R, Wagenpfeil S, Lunetta KL, Cupples A, Green RC, DeCarli C, Farrer LA, Kurz A, Journal of Alzheimer’s Disease, 17:855-862, 2009. PubMed Link
Caregiver-recipient closeness and symptom progression in Alzheimer disease: The Cache County Dementia Progression Study. Norton MC, Piercy KW, Rabins PV, Green RC, Breitner JCS, Ostbye T, Corcoran C, Welsh-Bohmer KA, Lyketsos CG, Tschanz JT, Journal of Gerontology: Psychological Sciences, 64B(5):560-568, 2009. PubMed Link
Disclosing the disclosure: Factors associated with communicating the results of genetic susceptibility testing for Alzheimer’s disease. Ashida S, Koehly LM, Roberts JS, Chen C, Hiraki S, Green RC, Journal of Health Communication, 14:768-784, 2009. PubMed Link
Perceptions of familial risk in those seeking a genetic risk assessment for Alzheimer’s disease. Hiraki S, Chen CA, Roberts JS, Cupples LA, Green RC, Journal of Genetic Counseling, 18:130-136, 2009. PubMed Link
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