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Reisa A. Sperling, MD, MMSc
Director, Center for Alzheimer's Research and Treatment
Professor of Neurology, Harvard Medical School
Director of Clinical Research, Memory Disorders Unit, Brigham and Women's Hospital
Director, Neuroimaging Program, Massachusetts Alzheimer's Disease Research Center
Reisa Sperling MD, MMSc is a neurologist, specializing in dementia and imaging research. Dr. Sperling's research is focused on the early diagnosis and treatment of Alzheimer's disease. Her recent work involves the use of functional MRI and PET amyloid imaging to study alterations in brain function during in aging and early Alzheimer's disease. She is the Principal Investigator on multiple NIH and Foundation grants to study the neural basis of memory impairment in MCI and AD, and the relationship of amyloid deposition to memory function.
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Dorene M. Rentz, PsyD
Co-Director, Center for Alzheimer Research and Treatment
Neuropsychologist, Brigham and Women's Hospital
Neuropsychologist, Massachusetts General Hospital
Associate Professor of Neurology, Harvard Medical School
Dorene Rentz, PsyD is a clinical neuropsychologist with a specialty in the early detection of cognitive changes associated with Alzheimer’s disease in individuals with high cognitive reserve. Her recent work involves developing an IQ-adjusted method that detects very early cognitive changes that might be predictive of prodromal Alzheimer's disease and, with Dr. Keith A. Johnson, validating this method using PET imaging. Dr. Rentz's clinical focus is on the neuropsychological evaluation of individuals with all types of behavioral and cognitive disorders.
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Gad A. Marshall, MD
Associate Medical Director of Clinical Trials, Center for Alzheimer Research and Treatment
Associate Neurologist, Brigham and Women’s Hospital
Assistant in Neurology, Massachusetts General Hospital
Instructor in Neurology, Harvard Medical School
Gad Marshall, MD is a behavioral neurologist at Brigham and Women's Hospital and Massachusetts General Hospital, focusing on clinical trials and neuroimaging biomarkers in Alzheimer's disease and its precursor stages. Dr. Marshall has a long-standing interest in clinical-pathologic and imaging correlates in Alzheimer's disease. His most recent work involves using clinical and biomarker data to assess the relationship between apathy, executive function and instrumental activities of daily living, cortical atrophy, in vivo amyloid deposition (PiB PET), cerebrospinal fluid (CSF) biomarkers (amyloid beta, total and phospho-tau), and synaptic integrity (FDG PET) in clinically normal elderly, mild cognitive impairment, and mild Alzheimer's disease dementia.
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Scott M. McGinnis, MD
Associate Neurologist, Brigham and Women's Hospital
Assistant in Neurology, Massachusetts General Hospital
Instructor in Neurology, Harvard Medical School
Scott McGinnis, MD is a staff neurologist at Brigham and Women's and Massachusetts General Hospitals. Dr. McGinnis clinical and research focus is on improving diagnostic and treatment methods in neurodegenerative dementias. Dr. McGinnis has a specific interest in clinical-pathological correlations in frontotemporal dementias and atypical, non-memory presentations of Alzheimer disease.
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Brendon Boot, MBBS
Associate Neurologist, Brigham and Women's Hospital
Assistant in Neurology, Massachusetts General Hospital
Instructor in Neurology, Harvard Medical School
Brendon Boot, MBBS is a Behavioral Neurologist with an interest in clinical and pathological correlations in dementia. He focuses on the early diagnosis and treatment of Dementia with Lewy Bodies, Alzheimer's Disease, and their combination. He also conducts research in multi-modal imaging and its utility in dementia diagnosis.
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Martha Vander Vliet, RN
Clinical Trials Nurse Manager, Brigham and Women's Hospital
Martha Vander Vliet joined Brigham and Women’s Hospital in 1985 and has been involved in research for the last 20 years. She is the Clinical Nurse Manager for the Center for Alzheimer Research and Treatment where she oversees day to day operations of clinical drug trials.
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Nancy Donovan, MD
Associate Psychiatrist, Brigham and Women's Hospital
Instructor in Psychiatry, Harvard Medical School
Nancy Donovan, MD is a geriatric psychiatrist with research interests in the pathophysiology of neuropsychiatric symptoms in Alzheimer's disease. Dr. Donovan is developing research examining social attachment, symptoms of loneliness, and Alzheimer's disease biomarkers.
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Natacha Lorius, BA
Research Assistant
Natacha Lorius graduated from Wellesley College with a B.A. in Anthropology. She works on several longitudinal studies on memory and aging occurring jointly between BWH and MGH. Natacha hopes to pursue a career in medicine.
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Kamolika Roy, BS
Research Assistant
Kamolika Roy graduated from Brandeis University with a B.S. in Neuroscience and Biology. She is currently working on several clinical trials at CART as well as longitudinal studies on memory and aging occurring jointly between BWH and MGH. Kamolika hopes to pursue a career in medicine.
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Susie Kim, BA
Susie Kim graduated from Wesleyan University with a double B.A. in Neuroscience & Behavior and Psychology. She is currently working on several clinical trials at CART and hopes to pursue a career in medicine.
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