The department of pathology operates several research cores for the Brigham Reseach institute, Dana Farber/Harvard Cancer Center, and Partners HealthCare.
The Specialized Histopathology (SHP) Core provides consultative and interpretive pathology
services including high quality, timely, state-of-the-art analysis of tissues obtained from a
variety of experimental systems, including rodents, fish, and monkeys. This Core also provides
professional expertise to assist in experimental design and the development and interpretation
of tests and their results.
The Tissue Microarray (TMA) Core generates tissue microarrays that allow hundreds of
tumors and samples to be evaluated on a single slide, maximizing precious tissue resources.
The Core also provides access to TMA Profiler, a Web-based database that facilitates data
dissemination and sharing.
The Cytogenetics Core provides insight into regions of the genome that are pathogenetic in
various neoplasms, leading to an understanding of the molecular pathways that play a role in
the biology of cancer. The Cytogenetics Core provides conventional metaphase karyotyping
and a comprehensive menu of molecular cytogenetic methods.
The virtual specimen locator core is set up to be a harvard-wide consortium to provide access to excess human tissues for research. It assists the investigator from formulating query, executing search, applying for IRB approval and retriving tissues from archives.