Aruna Pradhan, MD, MPH, MSc
Associate Epidemiologist, Brigham and Women's Hospital
Instructor in Medicine, Harvard Medical School
Staff Physician, VA Boston Healthcare System
Contact information:
Office address:
Division of Preventive Medicine
Brigham and Women's Hospital
900 Commonwealth Avenue East, 3rd Floor
Boston, Massachusetts 02215
Phone: 617-732-8777
FAX: 617-731-3843
E-mail: apradhan@partners.org
Primary research interests:
My primary research interest is the identification of novel biomarkers for prediction of diabetes and peripheral vascular disease in otherwise healthy populations. A central mechanism for the link between these disorders is insulin resistance, which has become a more recent interest of mine as it relates to the metabolic syndrome, inflammation, and other traditional cardiovascular risk factors.
Recent publications:
Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin-6, and risk of developing type 2 diabetes mellitus. JAMA 2001;286(3):327-34.
Pradhan AD, Rifai N, Ridker PM. Soluble intercellular adhesion molecule-1, Soluble vascular adhsion molecule-1, and the development of symptomatic peripheral arterial disease in men. Circulation 2002;106(7):820-5.
Pradhan AD, Manson JE, Rossouw JE, Siscovick DS, Mouton CP, Rifai N, Wallace RB, Jackson RD, Pettinger MB, Ridker PM. Inflammatory biomarkers, hormone replacement therapy, and risk of first myocardial infarction: prospective analysis from the Women's Health Initiative Observational Study. JAMA 2002;288(8):980-7.
Pradhan AD, Cook NR, Buring JE, Manson JE, Ridker PM. C-reactive protein is independently associated with fasting insulin in nondiabetic women. Arterioscler Thromb Vasc Biol 2002;23(4):650-5.
Pradhan AD, Manson JE, Meigs JB, Rifai N, Buring JE, Liu S, Ridker PM. Insulin, proinsulin, the proinsulin:insulin ratio and risk of developing type 2 diabetes mellitus in women. Am J Med 2002;114(6)438-44.
Rexrode KM, Pradhan AD, Manson JE, Buring JE, Ridker PM. Relationship of total and abdominal adiposity with CRP and IL-6 in women. Ann Epidemiol 2003;13(10):674-82.
Blake GJ, Pradhan AD, Manson JE, Williams GR, Buring J, Ridker PM, Glynn RJ. Hemoglobin A1c level and future cardiovascular events among women. Arch Intern Med 2004;164(7):757-61.
Pradhan AD, LaCroix AS, Trevisan M, Lewis CE, Langer RD, Hsia JA, Oberman A, Kotchen JM, Ridker PM. Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women. Circulation 2004;110(3):292-300.
Langer RD, Pradhan AD, Lewis CE, Manson JE, Rossouw JE, Hendrix SL, LaCroix AZ, Ridker PM. Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study. Thromb Haemost. 2005 Jun;93(6):1108-16.
Pradhan AD, Manson JE, Hendrix SL, Johnson KC, Wagenknecht LE, Haan MN, Weidner G, LaCroix AZ, Cook NR. Cross-Sectional Correlates of Fasting Hyperinsulinemia in post-menopausal women of different ethnic origin. Diabetic Medicine. 2006;23(1):77-85.
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