Howard D. Sesso, ScD
Associate Epidemiologist, Brigham and Women's Hospital
Assistant Professor of Medicine, Harvard Medical School
Contact information:
Office address:
Division of Preventive Medicine
Brigham and Women's Hospital
900 Commonwealth Avenue East, 3rd Floor
Boston, Massachusetts 02215
Phone: 617-732-8837
FAX: 617-734-1437
E-mail: hesso@rics.bwh.harvard.edu
Primary research interests:
Dr. Sesso's primary research interest is on the prevention of cardiovascular disease, focusing on blood pressure and hypertension, physical activity, and dietary factors including flavonoids, lycopene, and alcohol. He has established hypertension as a major endpoint in research studies (Physicians' Health Study, Women's Health Study) at the Division of Preventive Medicine, investigating behavioral, dietary, biochemical (lipid, inflammatory, and hemostatic), and genetic markers for the primary prevention of hypertension. Further, Dr. Sesso is serving as Principal Investigator for an R01 grant from the National Institutes of Health to examine several biochemical and genetic markers of incident hypertension in white and black women as part of a nested case-control study in the Women's Health Initiative. Dr. Sesso is actively involved in research on the primary prevention of cancer, considering various behavioral and dietary risk factors, as well as investigating novel dietary and plasma flavonoids for their associations with breast, colon, and lung cancer in women. Finally, as Project Director of the Physicians' Health Study and College Alumni Health Study, and active investigator with the Women's Health Study, Dr. Sesso is interested in the design, conduct, and methodology of randomized clinical trials and epidemiologic studies.
Recent publications:
Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM. C-reactive protein and the risk of developing hypertension. JAMA 2003;290:2945-2951.
Sesso HD, Buring JE, Norkus EP, Gaziano JM. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women. Am J Clin Nutr 2004;79:47-53.
Weinstein AR, Sesso HD, Lee IM, Cook NR, Manson JE, Buring JE, Gaziano JM. Relationship of physical activity vs body mass index with type 2 diabetes in women. JAMA 2004;292:1188-1194.
Lee IM, Sesso HD, Oguma Y, Paffenbarger RS Jr. The “Weekend Warrior” and risk of mortality. Am J Epidemiol 2004;160:636-641.
Sesso HD, Buring JE, Norkus EP, Gaziano JM. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men. Am J Clin Nutr 2005;81:990-997.
Sesso HD, Buring JE, Zhang SM, Norkus EP, Gaziano JM. Dietary and plasma lycopene and the risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2005;14:1074-1081.
Sesso HD, Buring JE, Chown MJ, Ridker PM, Gaziano JM. A prospective study of plasma lipids and hypertension in women. Arch Int Med 2005;165:2420-2427.
Halperin RO, Sesso HD, Ma J, Buring JE, Stampfer MJ, Gaziano JM. Dyslipidemia and the risk of incident hypertension in men. Hypertension 2006;47:45-50.
Sesso HD. Carotenoids and cardiovascular disease - What research gaps remain? Curr Opin Lipidol 2006;17:11-16.
Sesso HD, Gaziano JM, Glynn RJ, Buring JE. Value of an Endpoints Committee versus the use of nosologists for validating cause of death. Contemp Clin Trials 2006;27:333-339.