Clinical Pharmacology of Cardiovascular Agents Dr. Elliott Antman's research interests involve the clinical pharmacology of cardiovascular agents and their evaluation in randomized control trials. Dr. Antman is a Senior Investigator in the TIMI Study Group and is leading projects evaluating novel antithrombotic agents, especially for the management of acute coronary syndromes. Utilizing biostatistical techniques such as meta-analysis, the efficacy and safety of various agents are being evaluated. Dr. Antman is the immediate past chair of the ACC/AHA Task Force on Practice Guidelines and remains involved in the writing of the UA/STEMI and STEMI Guidelines. He is a member of the Board of Trustees of the American College of Cardiology and the Science Advisory and Coordinating Committee of the American Heart Association.
References:
Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE II, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, American College of Physicians, Society for Academic Emergency Medicine, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 2007;50:1-157; Circulation 2007;116:e148-e304.
Antman EM, Hand MM, Armstrong PW, Bates ER, Green LA, Halasyamani LK, Hochman JS, Krumholz HM, Lamas GA, Mullany CJ, Pearle DL, Sloan MA, Smith SC. July 2007 focused update of the ACC/AHA 2004 Guidelines for the Management of Patients with ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients with Percutaneous Coronary Intervention, Writing on Behalf of the 2004 STEMI Writing Committee. Circulation 2008;117:296-329.
Antman EM, Bennett JS, Daugherty A, Furberg C, Roberts H, Taubert KA. Use of nonsteroidal antiinflammatory drugs: an update for clinicians. A Scientific Statement from the American Heart Association. Circulation 2007;115:1634-1642.
Antman EM, Morrow DA, McCabe CH, Murphy SA, Ruda M, Sadowski Z, Budaj A, Lopez-Sendon JL, Guneri S, Jiang F, White HD, Fox KAA, Braunwald E., for the ExTRACT-TIMI 25 investigators. Enoxaparin versus unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction. N Engl J Med 2006;354:1477-1488.
Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, Neumann FJ, Ardissino D, De Servi S, Murphy SA, Riesmeyer J, Weerakkody G, Gibson CM, Antman EM, for the TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. New England Journal of Medicine 2007;357:2001-2015.
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