Educational and Training OpportunitiesRecent Publications During Fellowship
2006 Graduates
Sofia Ahmed, MD, MMSc
Ahmed SB, Hovind P, Parving HH, Rossing P, Price DA, Laffel LM, Lansang MC, Stevanovic R, Fisher ND, Hollenberg NK. Oral contraceptives, angiotensin-dependent renal vasoconstriction, and risk of diabetic nephropathy. Diabetes Care. 2005 Aug;28(8):1988-94.
Ahmed SB, Abi Rached JM, Singh AK, Charytan DM. A 39-year-old pregnant woman with polyuria and hypomagnesemia. Kidney Int. 2006 Mar;69(5):938-41
Javeed Ansari, MBBS
Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA. Costimulation and autoimmune diabetes in BB rats. Am J Transplant. 2006 May;6(5 Pt 1):894-902.
Fiorina P, Ansari MJ, Jurewicz M, Barry M, Ricchiuti V, Smith RN, Shea S, Means TK, Auchincloss H Jr, Luster AD, Sayegh MH, Abdi R. Role of CXC chemokine receptor 3 pathway in renal ischemic injury. J Am Soc Nephrol. 2006 Mar;17(3):716-23. Epub 2006 Feb 15.
Guleria I, Khosroshahi A, Ansari MJ, Habicht A, Azuma M, Yagita H, Noelle RJ, Coyle A, Mellor AL, Khoury SJ, Sayegh MH. A critical role for the programmed death ligand 1 in fetomaternal tolerance. J Exp Med. 2005 Jul 18;202(2):231-7.
Ansari MJ, Ahmad S, Kohli K, Ali J, Khar RK.Stability-indicating HPTLC determination of curcumin in bulk drug and pharmaceutical formulations. J Pharm Biomed Anal. 2005 Sep 1;39(1-2):132-8.
Ansari MJ, Tinckam K, Chandraker A. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med. 2005 May 12;352(19):2027-8; author reply 2027-8.
Ansari MJ, Sayegh MH. Clinical transplantation tolerance: the promise and challenges.
Kidney Int. 2004 May;65(5):1560-3. Review.
Ansari MJ, Abdi R. Emerging immunomodulatory therapies targeting the co-stimulatory pathways for the prevention of transplant rejection. IDrugs. 2003 Oct;6(10):964-9. Review.
Makhlouf L, Yamada A, Ito T, Abdi R, Ansari MJ, Khuong CQ, Winn HJ, Auchincloss H Jr, Sayegh MH. Allorecognition and effector pathways of islet allograft rejection in normal versus nonobese diabetic mice. J Am Soc Nephrol. 2003 Aug;14(8):2168-75.
Salama AD, Chitnis T, Imitola J, Ansari MJ, Akiba H, Tushima F, Azuma M, Yagita H, Sayegh MH, Khoury SJ. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med. 2003 Jul 7;198(1):71-8. Erratum in: J Exp Med. 2003 Aug 18;198(4):677.
Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, Yamazaki T, Azuma M, Iwai H, Khoury SJ, Auchincloss H Jr, Sayegh MH. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 2003 Jul 7;198(1):63-9.
Jeremy Duffield, MD, PhD
Duffield JS, Tipping PG, Kipari T, Cailhier JF, Clay S, Lang R, Bonventre JV, Hughes J. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis.Am J Pathol. 2005 Nov;167(5):1207-19.
Humphreys BD, Duffield JD, Bonventre JV.Renal stem cells in recovery from acute kidney injury.
Minerva Urol Nefrol. 2006 Mar;58(1):13-21.
Duffield JS, Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int. 2005 Nov;68(5):1956-61. Review.
Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005 Jul;115(7):1743-55. Epub 2005 Jun 2.
Muckova K, Duffield JS, Held KD, Bonventre JV, Sheridan AM. cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol. 2006 Jan;290(1):F70-9. Epub 2005 Jun 28.
Jesse Flaxenburg, MD
Flaxenburg JA, Melter M, Lapchak PH, Briscoe DM, Pal S. The CD40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves Ras and phosphatidylinositol 3-kinase. J Immunol. 2004 Jun 15;172(12):7503-9.
Lapchak PH, Melter M, Pal S, Flaxenburg JA, Geehan C, Frank MH, Mukhopadhyay D, Briscoe DM. CD40-induced transcriptional activation of vascular endothelial growth factor involves a 68-bp region of the promoter containing a CpG island. Am J Physiol Renal Physiol. 2004 Sep;287(3):F512-20. Epub 2004 May 12.
Andreas Herrlich, MD, PhD
Herrlich A, Leitch V, King LS. Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15799-804. Epub 2004 Oct 21
Jennifer Hunt, MD
Hunt JL, Pollak MR, Denker BM. Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation. J Am Soc Nephrol. 2005 Jun;16(6):1593-602. Epub 2005 Apr 20.
Sushrut Waikar, MD
Waikar SS, Wald R, Chertow GM, Curhan GC, Winkelmayer WC, Liangos O, Sosa MA, Jaber BL. Validity of international classification of diseases, ninth revision, clinical modification codes for acute renal failure. J Am Soc Nephrol. 2006 Jun;17(6):1688-94. Epub 2006 Apr 26.
Wald R, Waikar SS, Liangos O, Pereira BJ, Chertow GM, Jaber BL. Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm. J Vasc Surg. 2006 Mar;43(3):460-466; discussion 466.
Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol. 2006 Apr;17(4):1143-50. Epub 2006 Feb 22.
Kirtane AJ, Leder DM, Waikar SS, Chertow GM, Ray KK, Pinto DS, Karmpaliotis D, Burger AJ, Murphy SA, Cannon CP, Braunwald E, Gibson CM; TIMI Study Group. Serum blood urea nitrogen as an independent marker of subsequent mortality among patients with acute coronary syndromes and normal to mildly reduced glomerular filtration rates. J Am Coll Cardiol. 2005 Jun 7;45(11):1781-6.
June Yao, MD, PhD
Yao J, Le TC, Kos CH, Henderson JM, Allen PG, Denker BM, Pollak MR. Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol. 2004 Jun;2(6):e167.
Tsukaguchi H, Sudhakar A, Le TC, Nguyen T, Yao J, Schwimmer JA, Schachter AD, Poch E, Abreu PF, Appel GB, Pereira AB, Kalluri R, Pollak MR. NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele. J Clin Invest. 2002 Dec;110(11):1659-66.
2005 Graduates
Kenneth Christopher, MD
Christopher K, Liang Y, Mueller TF, DeFina R, He H, Haley KJ, Exley MA, Finn PW, Perkins DL. Analysis of the major histocompatibility complex in graft rejection revisited by gene expression profiles. Transplantation. 2004 Sep 27;78(6):788-98.
Colson YL, Christopher K, Glickman J, Taylor KN, Wright R, Perkins DL.Absence of clinical GVHD and the in vivo induction of regulatory T cells after transplantation of facilitating cells. Blood. 2004 Dec 1;104(12):3829-35.
Christopher K, Mueller TF, Liang Y, Finn PW, Perkins DL. Modulation of gene expression by alloimmune networks following murine heart transplantation. Mol Genet Genomics. 2004 Jul;271(6):687-96.
DeFina RA, Liang Y, He H, Haley KJ, Christopher K, Finn PW, Perkins DL.Analysis of immunoglobulin and T-cell receptor gene deficiency in graft rejection by gene expression profiles. Transplantation. 2004 Feb 27;77(4):580-6.
Liang Y, Christopher K, DeFina R, Cidado J, He H, Haley KJ, Finn PW, Perkins DL. Analysis of cytokine functions in graft rejection by gene expression profiles. Transplantation. 2003 Dec 27;76(12):1749-58.
Christopher K, Mueller TF, DeFina R, Liang Y, Zhang J, Gentleman R, Perkins DL. The graft response to transplantation: a gene expression profile analysis. Physiol Genomics. 2003 Sep 29;15(1):52-64.
DeFina R, Christopher K, He H, Mandelbrot D, Gu Y, Finn P, Perkins DL.Analysis of costimulation by 4-1BBL, CD40L, and B7 in graft rejection by gene expression profiles. J Mol Med. 2003 Oct;81(10):655-63.
Christopher K, Mueller TF, Ma C, Liang Y, Perkins DL. Analysis of the innate and adaptive phases of allograft rejection by cluster analysis of transcriptional profiles. J Immunol. 2002 Jul 1;169(1):522-30.
John Forman, MD
Forman JP, Bischoff-Ferrari HA, Willett WC, Stampfer MJ, Curhan GC.Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies. Hypertension. 2005 Oct;46(4):676-82.
Forman JP, Stampfer MJ, Curhan GC. Non-narcotic analgesic dose and risk of incident hypertension in US women. Hypertension. 2005 Sep;46(3):500-7.
Humphreys BD, Forman JP, Zandi-Nejad K, Bazari H, Seifter J, Magee CC. Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital. Am J Kidney Dis. 2005 Jul;46(1):143-6.
Yamada A, Salama AD, Sho M, Najafian N, Ito T, Forman JP, Kewalramani R, Sandner S, Harada H, Clarkson MR, Mandelbrot DA, Sharpe AH, Oshima H, Yagita H, Chalasani G, Lakkis FG, Auchincloss H Jr, Sayegh MH. CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo. J Immunol. 2005 Feb 1;174(3):1357-64.
Forman JP, Rimm EB, Stampfer MJ, Curhan GC. Folate intake and the risk of incident hypertension among US women. JAMA. 2005 Jan 19;293(3):320-9.
Forman JP, Tolkoff-Rubin N, Pascual M, Lin J. Hepatitis C, acute humoral rejection, and renal allograft survival. J Am Soc Nephrol. 2004 Dec;15(12):3249-55.
Forman JP, Lin J, Pascual M, Denton MD, Tolkoff-Rubin N. Significance of anticardiolipin antibodies on short and long term allograft survival and function following kidney transplantation. Am J Transplant. 2004 Nov;4(11):1786-91.
Forman JP. Hemofiltration and the prevention of radiocontrast-agent-induced nephropathy. N Engl J Med. 2004 Feb 19;350(8):836-8
Dirk Hentschel, MD
Hentschel DM, Bonventre JV. Novel non-rodent models of kidney disease. Curr Mol Med. 2005 Aug;5(5):537-46. Review.
Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol. 2005 May;288(5):F923-9.
Hentschel DM. Troponin T levels and acute coronary syndromes. N Engl J Med. 2002 Nov 21;347(21):1722-3; author reply 1722-3.
Hsu SI, Yang CM, Sim KG, Hentschel DM, O'Leary E, Bonventre JV. TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. EMBO J. 2001 May 1;20(9):2273-85.
Benjamin Humphreys, MD, PhD
Humphreys BD, Duffield JD, Bonventre JV. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol. 2006 Mar;58(1):13-21.
Humphreys BD, Forman JP, Zandi-Nejad K, Bazari H, Seifter J, Magee CC. Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital. Am J Kidney Dis. 2005 Jul;46(1):143-6.
Humphreys BD, Soiffer RJ, Magee CC. Renal failure associated with cancer and its treatment: an update. J Am Soc Nephrol. 2005 Jan;16(1):151-61.
Humphreys BD, Sharman JP, Henderson JM, Clark JW, Marks PW, Rennke HG, Zhu AX, Magee CC. Gemcitabine-associated thrombotic microangiopathy. Cancer. 2004 Jun 15;100(12):2664-70.
Hua (Jenny) Lu, MD, PhD
Lu H, Sun TX, Bouley R, Blackburn K, McLaughlin M, Brown D. Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2. Am J Physiol Renal Physiol. 2004 Feb;286(2):F233-43.
Krishna Polu, MD
Polu KR, Wolf M. Clinical problem-solving. Needle in a haystack. N Engl J Med. 2006 Jan 5;354(1):68-73. No abstract available. Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005 Jul;37(7):739-44. Epub 2005 May 27.
Jochen Reiser, MD, PhD
Moller CC, Pollak MR, Reiser J. The genetic basis of human glomerular disease.Adv Chronic Kidney Dis. 2006 Apr;13(2):166-73.
Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005 Jul;37(7):739-44. Epub 2005 May 27.
Eric Taylor, MD
Taylor EN, Curhan GC. Diet and fluid prescription in stone disease. Kidney Int. 2006 Jul 12; [Epub ahead of print]
Taylor EN, Hu FB, Curhan GC. Antihypertensive medications and the risk of incident type 2 diabetes. Diabetes Care. 2006 May;29(5):1065-70.
Taylor EN, Mount DB, Forman JP, Curhan GC. Association of prevalent hypertension with 24-hour urinary excretion of calcium, citrate, and other factors. Am J Kidney Dis. 2006 May;47(5):780-9.
Taylor EN, Curhan GC. Effect of dietary modification on urinary stone risk factors. Kidney Int. 2006 Mar;69(6):1093.
Taylor EN, Stampfer MJ, Curhan GC. Diabetes mellitus and the risk of nephrolithiasis. Kidney Int. 2005 Sep;68(3):1230-5.
Taylor EN, Stampfer MJ, Curhan GC. Fatty acid intake and incident nephrolithiasis. Am J Kidney Dis. 2005 Feb;45(2):267-74.
Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain, and the risk of kidney stones. JAMA. 2005 Jan 26;293(4):455-62.
Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol. 2004 Dec;15(12):3225-32.
Taylor EN, Curhan GC. Role of nutrition in the formation of calcium-containing kidney stones. Nephron Physiol. 2004;98(2):p55-63.
Taylor EN, Henderson JM, Rennke HG, Magee CC. Traumatic calcinosis cutis in a dialysis patient. Am J Kidney Dis. 2004 Aug;44(2):e18-21.
Kambiz Zandi-Nejad, MD
Mount DB, Kwon CY, Zandi-Nejad K. Renal urate transport. Rheum Dis Clin North Am. 2006 May;32(2):313-31, vi. Zandi-Nejad K, Luyckx VA, Brenner BM. Adult hypertension and kidney disease: the role of fetal programming. Hypertension. 2006 Mar;47(3):502-8.
Mercado A, Broumand V, Zandi-Nejad K, Enck AH, Mount DB. A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport. J Biol Chem. 2006 Jan 13;281(2):1016-26.
Zandi-Nejad K, Brenner BM. Primary and secondary prevention of chronic kidney disease. J Hypertens. 2005 Oct;23(10):1771-6.
Humphreys BD, Forman JP, Zandi-Nejad K, Bazari H, Seifter J, Magee CC. Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital. Am J Kidney Dis. 2005 Jul;46(1):143-6.
Nakada T, Zandi-Nejad K, Kurita Y, Kudo H, Broumand V, Kwon CY, Mercado A, Mount DB, Hirose S. Roles of Slc13a1 and Slc26a1 sulfate transporters of eel kidney in sulfate homeostasis and osmoregulation in freshwater. Am J Physiol Regul Integr Comp Physiol. 2005 Aug;289(2):R575-R585.
Zandi-Nejad K, Brenner BM. Strategies to retard the progression of chronic kidney disease. Med Clin North Am. 2005 May;89(3):489-509.
Zandi-Nejad K, Brenner BM. Preventing microalbuminuria in type 2 diabetes. N Engl J Med. 2005 Feb 24;352(8):833-4;
Zandi-Nejad K, Eddy AA, Glassock RJ, Brenner BM. Why is proteinuria an ominous biomarker of progressive kidney disease? Kidney Int Suppl. 2004 Nov;(92):S76-89. Review.
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