Staff Cardiologist, VA Boston Medical System
Dr. Bukhman's research focuses on the development and evaluation of interventions to prevent and treat heart disease in developing countries. He also works on the history of global tuberculosis and cardiovascular control.

Theodore Cohen, MD, MPH
Assistant Professor, Department of Medicine, Brigham and Women's Hospital

Associate Scientist, Division of Global Health Equity, Brigham and Women's Hospital
Dr. Cohen's research interests include the relationship between drug-resistance and mycobacterial fitness, risk factors for transmission, DOTS and DOTS-plus treatment outcome assessment, the effect of UV on reducing disease transmission, and the role of exogenous re-infection. He has worked in collaboration with clinical sites in resource-poor settings in Russia, South Africa, and the US.

Hamish Fraser, MbChb, MSc
Assistant Professor, Department of Medicine, Brigham And Women's Hospital
Instructor, Children’s Hospital Boston
Director of Informatics and Telemedicine, Program in Infectious Disease and Social Change, Department of Global Health and Social Medicine, Harvard Medical School
An expert in the development and application of telemedicine and teleradiology in resource-poor settings, Dr. Fraser designed a web-based system that allows users to import and modify images, add clinical data, and then compress, encrypt and email the information to consulting specialists. This allows archived data to be sent to a server and viewed over a secure web connection. Dr. Fraser is responsible for the design and oversight of the web-based medical record system that supports the management and monitoring of over 2000 patients in treatment in Peru and Haiti. He is the Principal Investigator on the informatics sub-project for the eradication of MDR-TB, funded by the Bill and Melinda Gates Foundation, and is currently performing clinical evaluation studies of the system, including the impact of medication order entry by nurses on data quality.

Jennifer Furin, MD, PhD
Instructor in Medicine, Department of Global Health and Social Medicine, Harvard Medical School
Associate Physician, Division of Global Health Equity and Division of Infectious Diseases, Brigham and Women's Hospital
Dr. Furin’s research focuses on the qualitative components of compliance with TB and HIV therapy. An expert on the social roots of infectious diseases, she conducts training, consultation, and research on the application of qualitative and ethnographic methods to the management of complex health interventions in resource-poor settings. Dr. Furin is responsible for the design and oversight of several ethnographic studies of health systems and the scale-up of community-based management of HIV and MDR-TB.

Thomas Gaziano, MD, MSc
Instructor, Department of Medicine, Brigham and Women's Hospital
Associate Physician, Division of Cardiology, Division of Global Health Equity, Brigham and Women's Hospital
Dr. Gaziano’s research focuses on cardiovascular diseases in developing countries. He is currently evaluating different schemes for risk stratification for cardiovascular disease (CVD) to compare the cost-effectiveness of different treatment options. He is refining a simple risk prediction tool that will identify those at high risk of CVD and facilitate appropriate clinical interventions.

Rocio Hurtado, MD
Instructor in Medicine, Harvard Medical School
Associate Physician, Division of Infectious Disease, Massachusetts General Hospital
Associate Physician, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Hurtado’s research focuses on MDR-TB co-infection with HIV in resource-limited settings. She is examining the outcomes, impact, and feasibility of combination antiretroviral therapy use in this population. She is also studying cross-resistance among fluoroquinolones and injectable agents used in the treatment of MDR-TB.

Louise Ivers, MD
Assistant Professor of Medicine, Harvard Medical School
Associate Physician, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Ivers' current  research is focused on the impact of targeted food assistance among patients with HIV infection, Prevention of Mother-to-Child Transmission of HIV (PMTCT) programs, and on addressing the human resources for health crisis facing many similarly poor countries globally.

J. Keith Joseph, MD
Instructor, Department of Medicine, Brigham and Women's Hospital
Associate Physician, Division of Global Health Equity, Brigham and Women's Hospital

Dr. Joseph’s research focuses on MDR-TB treatment in Lima, comparing the outcomes of individualized and standardized regimens. He is also engaged in operational research on the optimal use of surgery for patients with MDR-TB, the duration and dosing schedule of aminoglycosides, and the evaluation of treatment in children with MDR-TB disease.

Salmaan Keshavjee, MD, PhD
Medical Anthropologist, Division of Global Health Equity, Brigham and Women's Hospital
Assistant Professor in Medicine, Harvard Medical School
Dr. Keshavjee’s research spans three areas: (1) modernity, social institutions, civil society, and health in the Middle East and Central Asia; (2) health-sector reform and access to health care and medical technology in transitional societies, with a special focus on countries of the former Soviet Union; and (3) the role of non-governmental organizations in globalization and the formation of trans-border civil society. His methodological expertise is in ethnography, participant-observation, and qualitative interview techniques. This background is particularly germane to the DSMHI’s work in Tomsk, Siberia, the first systematic effort to treat MDR-TB in the Russian Federation in accordance with international clinical practice standards.

Serena Koenig, MD
Instructor in Medicine, Harvard Medical School
Associate Physician, Division of Global Health Equity, Brigham and Women’s Hospital
Associate Physician, Division of Infectious Diseases, Massachusetts General Hospital
Dr. Koenig’s research analyzes outcomes from a model program that combines HIV and TB treatment with economic and psychosocial support. She is studying adherence, health outcomes, and costs of different HIV treatment strategies at the Cornell University GHESKIO site in Port-au-Prince, Haiti. The goal is to improve HIV treatment outcomes in urban settings where treatment is currently not directly observed.

Joia Mukherjee, MD, MPH
Assistant Professor in Medicine, Harvard Medical School
Associate Physician, Division of Global Health Equity and Division of Infectious Diseases, Brigham and Women’s Hospital
Associate Physician, Division of Infectious Diseases, Massachusetts General Hospital
Medical Director, Partners In Health
Dr. Mukherjee’s research interests focus on developing predictive algorithms to determine the spectrum of signs, symptoms, and clinical illnesses in persons presenting for HIV-related care in rural Haiti, and to determine the positive predictive values of the illnesses for CD4 count. She is also studying the clinical outcomes of TB treatment in patients receiving highly active antiretroviral therapy (HAART) for HIV as well as TB therapy versus those who are treated for TB alone.

Michael Rich, MD, MPH
Instructor, Department of Medicine, Brigham and Women's Hospital
Dr. Rich is the primary author of DOTS-Plus at a Glance: Protocols and Guidelines for the Treatment and Management of Multidrug-Resistant Tuberculosis and a member of the WHO’s Green Light Committee Working Group on DOTS-Plus for MDR-TB. His research interests range from identifying effective methods to reduce alcohol-related illness and risk behaviors in persons with chronic infectious disease living in resource-poor settings, to randomized prospective studies of protocols for the delivery of DOT-HAART.

Sonya Shin, MD
Assistant Professor of Medicine, Harvard Medical School
Associate Physician, Division of Global Health Equity and Division of Infectious Diseases, Brigham and Women’s Hospital
Dr. Shin’s research compares time to culture conversion among high-risk patients receiving individualized MDR-TB therapy based on rapid methods of drug susceptibility testing (DST) to time to culture conversion among those receiving individualized therapy based on conventional DST. Shin is interested in analyzing treatment outcome by risk category, and also in employing decision and cost-effectiveness analysis to determine which high-risk groups would benefit from early screening for MDR-TB infection.


Non-Clinical Research Faculty

Mercedes C. Becerra, ScD
Assistant Professor, Department of Global Health and Social Medicine, Harvard Medical School
Epidemiologist, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Becerra’s research is focused on the effects of resistance mutations on the transmissibility of M. tuberculosis, the occurrence and management of secondary cases of active TB and MDR-TB in household contacts, and the prevention of active TB and MDR-TB disease through preventive therapy among those with latent infection.

Arachu Castro, PhD, MPH
Assistant Professor of Social Medicine, Department of Global Health and Social Medicine, Harvard Medical School
Medical Anthropologist, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Castro's research focuses on infectious diseases (AIDS, TB, and dengue) and reproductive health. She studies how social inequalities are embodied as differential risk for pathologies common among the poor and how health policies may alter the course of epidemic disease and other pathologies afflicting populations living in poverty. Castro is currently involved in quality improvement initiatives for complex health interventions in resource-poor settings in the Caribbean and in Africa.

Carole Mitnick, ScD
Instructor in Social Medicine, Department of Global Health and Social Medicine, Harvard Medical School
Epidemiologist, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Mitnick conducts clinical outcomes research in MDR-TB. Her research interest is in the clinical epidemiology of chronic infectious diseases and its use for informing the delivery and evaluation of effective treatment in poor settings. She is the lead investigator on a large clinical-outcomes and cost-effectiveness study of the drug-resistant TB treatment strategies used in Peru in 1995-2002. Dr. Mitnick is interested in the application of novel analytic methods to MDR-TB outcomes research and is working on the identification of surrogate endpoints for MDR-TB therapy. She is PI of a clinical trial comparing the third-generation fluoroquinolone gatifloxacin to ciprofloxacin in MDR-TB therapy.

Mary Kay Smith-Fawzi, DSc
Instructor, Department of Global Health and Social Medicine, Harvard Medical School
Epidemiologist, Division of Global Health Equity, Brigham and Women’s Hospital
Dr. Smith-Fawzi has studied depression and the progression of HIV in over 1,000 HIV-positive women in Tanzania, where she and her colleagues observed an increased risk of HIV disease progression among women who were depressed compared with those who were not depressed at baseline. For the past five years, she has served as the Co-I of Dr. Farmer’s Fogarty-funded grants on STDs in rural Haiti. Dr. Smith-Fawzi has focused on study design, data collection procedures, statistical analyses, and publication of manuscripts in collaboration with colleagues and trainees in Haiti.