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Research Summary

Our research primarily focuses on modulation of intestinal function. We are examining the physiological regulation of the intestinal sodium transporter SGLT1 in health and disease, to help develop novel therapeutic approaches for altering intestinal absorptive capacity of glucose in disease states such as obesity and diabetes. Studies are performed in vivo (rodents and humans) and in vitro.

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Funding

1. NIH-NIDDK 5R)1DK047326 (PI: Ashley, 09/1996 - 09/2008) -- "Surgery and intestinal adaptation"

2. Tsumura USA (PI: Ashley, 05/2006 - 05/2008) -- "A randomized, 2-stage, placebo-controlled, open-label tolerability and efficacy study of TU-100 for the treatment of postoperative ileus in patients undergoing laparotomy for bowel resection."

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Publications

To access Dr. Stanley Ashley's publications, please click here.

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Stanley Ashley
MD

Vice Chair of Department of Surgery
Surgical Director of Center for Surgery and Public Health

Clinical Profile & Contact Information

Research Interests

Nutrition/Metabolism
Gene Silencing/Expression
Membrane Transport
Drug Development & Delivery Systems
Protein Metabolism
Metabolic Imaging using MRI