|  Research Summary  |  Funding  |  Publications  |
|  Back to Division of Otolaryngology  |

Research Summary

Our collaborative research group is interested in a wide range of topics concerning chronic rhinosinusitis. One major focus concerns the epidemiology and accuracy of diagnosis in chronic rhinosinusitis. We are conducting several prospective studies looking at patients' symptoms reporting, pathological findings and radiographic findings to determine cost efficient efficient and accurate diagnostic protocols for chronic rhinosinusitis. We are also examining psychological comorbidities in chronic rhinosinusitis and their influence on diagnosis.

A second major focus is assessment of clinical outcomes after endoscopic sinus surgery for chronic rhinosinusitis. In particular, we are examining predictive factors that lead to recurrent disease both in early and late failures after endoscopic sinus surgery in an effort to determine optical medical treatment strategies after surgery. This includes examination of molecular markers and host phenotype. We will be expanding these projects with inter-departmental collaboration between otolaryngology, allergy and immunology to pool resources to analyze molecular mechanisms at the tissue level that produce inflammation in chronic rhinosinusitis. Also incorporated in this research is the prospective, multi-institutional analysis of quality-of-life impact of chronic rhinosinusitis and outcomes after endoscopic sinus surgery.

Back to the top

Funding

1. Private Philanthropy (PI: Bhattacharyya, 01/2007 - 12/2008) -- "Mechanisms of recurrent disease and inflammation in chronic sinusitis."

The major goals of this project are to determine the underlying inflammatory mediators and local cellular interactions within the sinus and sinonasal mucosa leading to recurrence of chronic sinusitis and sinonasal polyposis.

2. Schering Plough Industry Grant (PI: Bhattacharyya, 05/2005 - Present) -- "Accuracy of diagnosis in chronic rhinosinusitis."

The primary goal of this project is to determine clinical and epidemiological criteria for the accurate diagnosis of chronic rhinosinusitis across medical disciplines and differing patient populations.

3. Arthrotec Corporation (PI: Bhattacharyya, 04/2005 - Present) -- "Clinical Effectiveness of Plasma Beam Coblation of Nasal Tissue"

A major goal of this project is to determine the clinical effectiveness of a novel form of plasma beam soft tissue inflation for nasal turbinates and sinonasal polyps. Of particular interest is the safety, durability and repeatability of this technique in the outpatient setting for recurrent sinonasal disease and allergic rhinitis.

Back to the top

Publications

To access Dr. Neil Bhattacharyya's publications, please click here.

Back to the top

Neil Bhattacharyya
MD, FACS

Associate Chief of Otolaryngology 

Clinical Profile & Contact Information

Research Interests

Chronic Rhinosinusitis