The End of the Beginning"
Laurie Glimcher, MD
President and CEO,
Dana-Farber Cancer Institute
Richard and Susan Smith Professor, Medicine, HMS
Three learning objectives:
1) Introduction and overview of cancer immunotherapy.
2) Overview of the ER Stress Response.
3) Summary of the function of the IRE1/XBP1 arm of the ER Stress Response in both the tumor and in controlling immune responses in the tumor microenvironment.