Genomic Medicine

Genomic Medicine at Brigham and Women’s Hospital (BWH) is dedicated to harnessing the power of genomic sequencing—revealing the DNA makeup of an organism—to transform patient care. Our multidisciplinary team of world-class physicians, genetic counselors, bioinformaticians and research scientists collaborates with experts throughout BWH and externally to provide exceptional care for patients with a wide variety of medical problems that are suspected or known to have a genetic basis. 

An important component of our mission to integrate genomics into clinical care is the advancement of research discovery and the translation of genomic advances into clinical practice. We work closely with translational and basic science research initiatives at BWH including:

• Brigham Research Institute Genomic Center
• Genomes2People Research Program 
• NIH-funded Undiagnosed Diseases Network

Make an Appointment

The Genomic Medicine outpatient clinic is located at BWH’s main campus in Boston. To make an appointment or for additional information, please call (617) 525-6600 or email

Refer a Patient

We are available to see patients for whom genomic sequencing is being considered or those in whom sequencing has already been performed. We invite and encourage referring providers to participate in clinic evaluation and case conference discussions of their patients.  

To refer a patient or for more information about our services, please call (617) 525-6600 or email  

Genomic Medicine Team

Our multidisciplinary team holds weekly case conference meetings to review patient medical and family histories and corresponding genomic data in preparation for patient visits. This also provides a forum for institutional colleagues to seek input on questions around genetic diagnosis, genetically-informed management, the need for genome sequencing, and interpretation of genome sequencing results. 

Genomic Medicine Clinical Services

The Genomic Medicine outpatient clinic is an integrated, multidisciplinary clinical service located at BWH’s main campus in Boston. We combine comprehensive medical and family history assessment with expertise in genomic sequence interpretation to aid in disease diagnosis, inform medical management, and support disease prevention for individuals and their families.   

The clinic leverages the expertise of specialists throughout the hospital and coordinates with existing genetics clinics:

What to Expect

We create a customized clinic visit for each patient. Prior to the clinic visit, a member of the genomic medicine team will gather additional information and a family history from the patient and/or referring provider. Patients will be presented at one of our weekly multidisciplinary case conference meetings to determine what clinical specialties and testing will be involved in the clinic visit. 

Because interpretation of genomic results is often aided by clinical evaluation and analysis of genomic sequence from family members, our team may also offer appointments for members of a patient’s family. While involvement of family members for evaluation or blood draw is often requested, it is not required. 

During the clinic visit, a patient may see one or more physicians and a genetic counselor.  We make our best effort to coordinate patient and family visits to occur on the same day in the same clinic space. For some patients, additional information or other testing is recommended before a decision about the utility of sequencing can be determined. For others, genomic sequencing is recommended outright. Our team will answer questions and address concerns you may have about this type of testing.

During your visit, we may also discuss various research opportunities with you. Research participation is always voluntary.

Genomic Medicine Resources

Genetics Home Reference

National Human Genome Research Institute

ClinGen – The Clinical Genome Resource


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