Brigham and Women’s Immune Deficiency Clinic

The Immune Deficiency Clinic is a research and patient-care group of allergy and immunology experts devoted to advancing the health of patients with primary and acquired immune deficiency. The focus of patient care includes developing evidence-based and scientifically-informed individualized management plans.

How We Can Help

We see patients with a broad range of immune deficiencies and immune dysregulation. These conditions include:

  • Primary immunodeficiencies such as common variable immune deficiency, chronic granulomatous disease, hyper immunoglobulin E syndromes
  • Secondary immunodeficiencies due to therapy for autoimmune or oncologic conditions
  • We also evaluate individuals with abnormal or concerning immunological laboratory values for further immune evaluation.
  • We offer advanced diagnostic testing of immune function.
  • We are able to develop scientifically-informed therapeutic options in circumstances where clinical trial data are rare or absent.
  • Patients in the immune deficiency clinic have opportunities to be involved in research aimed to shed light on relationships between immune fitness and autoimmunity.
  • We collaborate closely with several other specialties, including Hematology/Oncology, Rheumatology, Pulmonary, Infectious Disease, Genetics, and Gastroenterology.

What Sets Us Apart

The integration of clinical care and research programs offers deeper diagnostic opportunities and treatment options, including personalized and precision medical options.

Our Experts

Dr. Duane Wesemann heads a laboratory of antibody development and lymphocyte dynamics. He is a decorated researcher with Career Development Awards from the American Academy of Allergy, Asthma, and Immunology, and the Clinical Immunology Society. His group addresses fundamental immunologic questions including how antibodies are generated.

Dr. David Sloane is a decorated educator and highly sought after expert in immune regulation. They cofounded the BWH immune deficiency clinic, which has seen a steady increase in referrals since its inception in 2010.

Schedule an Appointment

Call (617) 732-9850 to make an appointment. The team is available to answer your calls

Monday – Friday, 8:30am- 4:30pm. To fast track your appointment, please ask the attendant on the phone to put in a request to the physicians.

Refer a Patient

If you are a referring Physician and would like more information on the referral process, please contact our staff at (617) 732-9850.

Our Location

Brigham and Women’s Hale Building for Transformative Medicine
60 Fenwood Road
2nd Floor
Boston, MA 02115

Phone: (617) 732-9850
Fax: (617) 731-2748

Learn more about Brigham and Women's Hospital

For over a century, a leader in patient care, medical education and research, with expertise in virtually every specialty of medicine and surgery.

About BWH