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Glioblastoma is a type of cancerous (malignant), fast-growing tumor that originates in the brain and, less frequently, in the spinal cord. Glioblastomas are the most advanced form of a group of brain tumors called gliomas.
Glioblastomas are tumors that arise from astrocytes, which are the star-shaped cells that make up the supportive tissue of the brain. These tumors are usually highly malignant (cancerous) because the cells reproduce quickly and because glioblastomas are supported by a large network of blood vessels. In addition, because glioblastomas have finger-like tentacles, they are very difficult to completely remove surgically, especially when they grow near parts of the brain that control important functions.
Symptoms vary based on size and location of the tumor. They may include:
Diagnosis includes a neurological exam with a physician for balance, reflexes, vision, hearing, and other neurological function and brain imaging (including MRI, CT, and PET).
Glioblastomas can be difficult to treat because the tumors contain many different types of cells, some of which may respond well to certain therapies, while others do not. Therefore, glioblastoma treatment may combine several different approaches, including:
Despite significant advances in treating glioblastomas, they frequently recur and require ongoing imaging and treatment.
Learn more about glioblastoma treatment at Brigham and Women’s Hospital.
When facing an aggressive form of cancer like glioblastoma, it is critical to start your treatment at a center highly experienced in treating the condition. The neurosurgeons at Brigham and Women's Brain Tumor Center work closely with 200 to 300 glioblastoma patients each year—a high volume of experience that allows for exceptional care. Our neurosurgeons, in collaboration with neuro-oncologists, radiation oncologists, and other cancer specialists, will develop a care plan that accounts for your individual cancer and incorporates the most up-to-date treatment options.
As a patient at Brigham and Women's Hospital, you can count on:
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