Resources and Environment for Clinical Investigation

The Harvard Catalyst is a pan-Harvard University enterprise dedicated to improving human health. Harvard Catalyst works with Harvard schools and the academic healthcare centers (hospitals) to build and grow an environment where discoveries are rapidly and efficiently translated to improve human health. Harvard Catalyst was founded in May 2008. The resources of the Harvard Catalyst are available to all faculties at Harvard regardless of their institutional affiliation or academic degree.

The Center for Clinical Investigation (CCI) at Brigham and Women's Hospital provides inpatient and outpatient units for clinical research, in addition to other resources.  The inpatient unit is located on the ninth floor of the Hospital Towers, (6,000 square feet).  The inpatient facility includes the Nutrition Core, Nursing Services, Specimen Processing and Phlebotomy, Intensive Physiologic Monitoring Unit and Standard Bed Units. In addition, there are resources in the Neonatal Intensive Care Unit, located in the Center for Women and Newborns.

There are three Ambulatory research units associated with the CCI.  The Ambulatory Clinical Care unit is located at 221 Longwood Avenue, (2,400 square feet).  This includes a waiting room, 5 examination rooms, phlebotomy chair, staff workstation area, a metabolic kitchen, patient dining room, conference area, and a specimen processing and storage laboratory. 

The Clinical Trial Center is located on the fourth floor of the original Peter Bent Brigham Hospital, (1,800 square feet). This space includes a reception area, four exam rooms, phlebotomy chair, and a small laboratory for processing and storing specimens.  There is also an Infusion Center with four rooms equipped to deliver controlled-rate intravenous infusions to patients with appropriate hemodynamic monitoring.

The Clinical Trials Hub is located on the third floor of the Building for Transformative Medicine (1,466 square feet). This space includes a reception area, three exam rooms, a consult room, an infusion suite, and a small laboratory for processing and storing specimens.  There is also an Infusion Suite with three bays equipped to deliver controlled-rate intravenous infusions to patients with appropriate hemodynamic monitoring.

There is a network of over 25 computers that make up the C-SMART system used on the Intensive Physiologic Monitoring Unit.  The focus of the Informatics Core is to provide 24-hour availability of all user files, network programs, and data files to the Informatics Core, Core Lab, Dietary, Nursing, and Administration. 

The Nutrition Core operates dietary service seven days per week, allowing continuous research support for all studies from 7:00 a.m. - 6:30 p.m.  There are currently two metabolic research kitchens. The inpatient 9A kitchen services both inpatient and outpatient studies.  The satellite kitchen is located at the Ambulatory Physiologic Research unit and has the capacity to provide meals to outpatient studies.

The Biostatisticians provide statistical collaboration by performing the analyses and writing the methods and results sections of manuscripts, and answering any questions that arise in the editorial review process.  Informal consultations are also available.

The Research Coordinator Network (RCNet) provides investigators with a source for reliable and experienced research coordinators for clinical investigation. Coordinators are on hand to work simultaneously on a variety of protocols throughout the hospital, on a part- or full-time basis.