Multidisciplinary Approach to Understand the Etiology and Pathobiology of Kidney Stone Disease to Improve Diagnosis, Prognosis and Treatment
Kidney stone disease (nephrolithiasis) affects more than 19 million U.S. adults and tens of millions more worldwide. Although rarely fatal, the morbidity and costs are substantial. A large number of modifiable risk factors for kidney stones have been identified, including diet, fluid intake, and other lifestyle factors.
Current research
Investigators at the Channing Division of Network Medicine (CDNM) have built a comprehensive research strategy to:
- Study the epidemiology of nephrolithiasis
- Identify key dietary factors associated with risk of nephrolithiasis
- Identify the urinary risk factors for nephrolithiasis
- Study other health conditions associated with kidney stone disease
We apply a multidisciplinary approach to understand the etiology and pathobiology of nephrolithiasis to improve diagnosis and prognosis, and to develop therapeutics for treatment.