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Seminars in Molecular and Genomic Medicine

Seminars in Molecular and Genomic Medicine is a key educational and research event of the Division of Genetics and features distinguished speakers from local, national, and foreign universities or other research institutions. Seminar topics span basic research as well as translational and clinical genetics research, and include experimental and computational studies.

Seminars are held on Wednesdays as listed in the schedule below at 4 PM in the main seminar room (NRB457) on the 4th floor of the Harvard Medical School New Research Building at 77 Avenue Louis Pasteur in Boston, MA. Refreshments are served at 3:45 outside the seminar room.

The seminars are widely advertised by direct mailings and to all major departments at Harvard, its affiliated hospitals and MIT. To be added to the Seminars in Molecular and Genomic Medicine email list for seminar announcements, please email: Paloma Sanchez.

2019-2020 Seminar Speaker Schedule

Seminars will start in the Fall of 2019 and will be announced over the summer. Please check back regularly for updates.

Prior Seminars in Molecular and Genomic Medicine

2017-2018 Seminar Speaker Schedule

Steve Horvath, Ph.D., Sc.D.
UCLA David Geffen School of Medicine
Department of Human Genetics
Professor of Human Genetics & Biostatistics
April 4, 2018
“Epigenetic clock: causes and consequences”

Job Dekker, PhD
Howard Hughes Medical Institute
Department of Biochemistry and Molecular Pharmacology
University of Massachusetts Medical School
Professor and co-director, Program in Systems Biology
May 16, 2018
“Folding, unfolding and refolding of genomes”

Ernest Fraenkel
Department of Biological Engineering
Massachusetts Institute of Technology
June 13, 2018

2015-2016 Seminar Speaker Schedule

co-sponsored by the Translational Genomics Research Seminar Brigham Research Institute
Seminars in Molecular and Genomic Medicine (formerly known as Molecular Medicine Seminar Series - MMSS) received funds in 2013-2015 from Agilent, Illumina, and Merck
Jeremy Luban , M.D.
University of Massachusetts Medical School
February 14, 2018
Dendritic cell response to pathogens and tolerogens as a groovy model for understanding human transcriptional regulation
David Walt , Ph.D.
Brigham and Women’s Hospital
Wyss Institute for Biologically Inspired Engineering
Howard Hughes Medical Institute
February 14, 2018
Single Molecule Arrays: From Fundamental Biochemistry to Diagnostics
Stuart Orkin, M.D.
Harvard Medical School, Howard Hughes Medical Institute
David G. Nathan Distinguished Professor of Pediatrics
January 10, 2018
Genetics and epigenetics of the human fetal hemoglobin switch 
and prospects for its direct manipulation
Tuuli Lappalainen, Ph.D.
Assistant Investigator and Assistant Professor
New York Genome Center & Columbia University
December 13, 2017
Functional variation in the human genome: lessons from the transcriptome
Laurie Boyer, Ph.D.
Massachusetts Institute of Technology
Irvin and Helen Sizer Career Development Associate Professor of Biology
November 8, 2017
Reprogramming a broken heart
Jason D. Buenrostro, Ph.D.
Broad Institute of Harvard and Massachusetts Institute of Technology
Broad Institute Fellow
October 11, 2017
From ensembles to single-cells: A window into cis- and trans- epigenomic variability
Professor Harmen Bussemaker, Ph.D.
Columbia University
Department of Biological Sciences 
Department of Systems Biology 
April 26, 2017
Accurate Quantification of Protein-DNA Recognition from Sparse Sequencing Data
Luca Giorgetti, Ph.D.
Group Leader
Friedrich Miescher Institute (FMI)
for Biomedical Research
Basel, Switzerland
February 16, 2017
Structure vs Function: A quantitative analysis of chromosome structure and long-range transcriptional regulation in mammals
Heidi Mcbride, Ph.D.
Canada Research Chair in Mitochondrial Cell Biology
Professor, McGill University
June 3, 2016
Uncovering the physiological role of mitochondrial SUMOylation
Olivier Pouquié, Ph.D.
Brigham and Women's Hospital
Department of Genetics
April 6, 2016
Making muscle in vivo and in vitro
Levi Garraway, M.D., Ph.D.
Dana-Farber Cancer Institute
Department of Medical Oncology
March 30, 2016
From Genome Biology to Cancer Precision Medicine
Allon Moshe Klein, Ph.D.
Harvard Medical School
February 24, 2016
Stochastic fate choice and single cell analysis of stem cell populations
Joseph Thornton, Ph.D.
University of Chicago
December 9, 2015
Gordon L. Hager, Ph.D.
Chief and Senior Investigator
Laboratory of Receptor Biology and Gene Expression
Center for Cancer Research
National Cancer Institute
November 18, 2015
A dynamic Equilibrium Model for Enhancer Function
Matthew Stephens, Ph.D. 
Professor, Department of Human Genetics and Department of Statistics
University of Chicago
October 21, 2015
Genetic association analysis of multiple phenotypes and/or multiple groups
Geoffrey S. Ginsburg, M.D., Ph.D.
Director, Center for Applied Genomics & Precision Medicine
Duke University School of Medicine
September 9, 2015
Novel Genomic Paradigms for Early Detection of Acute and Chronic Disease
Myles Brown, M.D.
Dana-Farber Cancer Institute
May 13, 2015
Genetics and Epigenetics of Hormone Dependent Cancers
Kiran Musunuru, M.D., Ph.D.
Harvard University Department of Stem Cell and Regenerative Biology
April 29, 2015
From genotype to phenotype to therapeutics at cardiovascular disease loci

Cynthia Morton, Ph.D.
Brigham and Women’s Hospital/ Harvard Medical School
March 11, 2015
Looking Under the Lamppost: Genome Annotation through Sequencing Balanced

Feng Zhang, Ph.D.
Broad Institute and Massachusetts Institute of Technology
January 21, 2015
Genome Engineering: Technologies and Applications

Bing Ren, Ph.D.
University of California San Diego
November 19, 2014
More than beads on a string: Exploring Gene Regulation in the 3D genome

Angela DePace, Ph.D.
Harvard Medical School
October 15, 2014
Shadow enhancers enable complex transcriptional circuit in Drosophila embryos

Jason M. Johnson, Ph.D.
Associate Vice President
June 18, 2014
Data and information sciences in pharmaceutical research

Haiyuan Yu, Ph.D.
Assistant Professor
Department of Biological Statistics and Computational Biology 
Weill Institute for Cell and Molecular Biology 
Cornell University
June 11, 2014
Understanding molecular mechanisms of human disease mutations through 3D protein network models

Ken Zaret, Ph.D.
Joseph Leidy Professor in the Department of Cell and Developmental Biology
University of Pennsylvania School of Medicine
May 28, 2014
Mechanisms of Cell Programming and Reprogramming
Tian Xu, Ph.D.
Professor of Genetics
Yale School of Medicine
May 21, 2014
Growth and Size Regulation in Development & Disease

Xiaole Shirley Liu, Ph.D.
Professor, Biostatistics and Computational Biology
Dana-Farber Cancer Institute
May 14, 2014
Integrating High Throughput Data to Infer Function of Chromatin Regulator and LncRNAs in Cancer

Caroline Fox, M.D.
Associate Clinical Professor of Medicine
Brigham and Women's Hospital 
Framingham Heart Study
April 16, 2014
Using Genomic Studies to Provide Insights into Kidney Function

Nicholas Katsanis, Ph.D.
Director, Center for Human Disease Modeling
Professor of Cell Biology
Brumley Distinguished Professor of Pediatrics
Duke University
March 26, 2014
Modeling the Morbid Human Genome

Derrick Rossi, Ph.D.
Assistant Professor of Stem Cell and Regenerative Biology
Children's Hospital, Boston
March 5, 2014
Reprogramming committed blood cells to induced hematopoietic stem cells with defined factors

Evan Rosen, M.D., Ph.D.
Associate Professor of Medicine
Harvard Medical School
Beth Israel Deaconess Medical Center
February 26, 2014
Epigenomic and transcriptional analysis of adipose biology

Vamsi K. Mootha, M.D.
Professor of Systems Biology
Massachusetts General Hospital
Harvard Medical School
January 22, 2014
Mitochondrial parts, pathways, and pathogenesis

Suzanne Gaudet, Ph.D.
Assistant Professor of Genetics
Dana-Farber Cancer Institute
January 15, 2014
Leveraging cell-to-cell variability to understand signal transduction circuits

Keith Joung, M.D., Ph.D.
Associate Professor of Pathology
Massachusetts General Hospital
December 11, 2013
Targeted Genome and Epigenome Editing Using TALE and CRISPR-Cas Technologies

Jay Shendure, M.D., Ph.D. 
Associate Professor of Genome Sciences 
Department of Genome Sciences 
University of Washington 
February 8, 2012 
Next-Generation Human Genetics

Didier Stainier, Ph.D. 
Professor, Department of Biochemistry & Biophysics
University of California, San Francisco
December 15, 2011
Development of Cardiac Form and Function in Zebrafish

Michel Georges, D.V.M., Ph.D.
Unit of Animal Genomics GIGA-R & Faculty of Veterinary Medicine 
University of Liege, Belgium 
November 10, 2011 
The long and winding road from correlation to causation in the genetics of human diseases: lessons from animal genetics

Yang Chai D.D.S., Ph.D. 
George and MaryLou Boone Professor 
Director, Center for Craniofacial Molecular Biology 
Associate Dean of Research
Ostrow School of Dentistry 
University of Southern California 
September 26, 2011 
TGF-beta signaling mechanism in regulating craniofacial development and tissue regeneration

Robert Green, M.D., M.P.H. 
Boston University School of Medicine and Public Health 
October 27, 2010 
Translational Genomics and Health Outcomes: A New Research Discipline

Karen Avraham, Ph.D. 
Chair of the Department of Human Molecular Genetics and Biochemistry
Tel Aviv University School of Medicine
October 7, 2010
microRNA Regulation in the Inner Ear: Implications for Deafness