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Seminars in Molecular and Genomic Medicine

Seminars in Molecular and Genomic Medicine is a key educational and research event of the Division of Genetics and features distinguished speakers from local, national, and foreign universities or other research institutions. Seminar topics span basic research as well as translational and clinical genetics research, and include experimental and computational studies.

Seminars are held on Wednesdays as listed in the schedule below at 4 PM in the main seminar room (NRB457) on the 4th floor of the Harvard Medical School New Research Building at 77 Avenue Louis Pasteur in Boston, MA. Refreshments are served at 3:45 outside the seminar room.

The seminars are widely advertised by direct mailings and to all major departments at Harvard, its affiliated hospitals and MIT. To be added to the Seminars in Molecular and Genomic Medicine email list for seminar announcements, please email: Paloma Sanchez.

Prior Seminars in Molecular and Genomic Medicine

2017-2018 Seminar Speaker Schedule

Steve Horvath, PhD, ScD
UCLA David Geffen School of Medicine
Department of Human Genetics
Professor of Human Genetics & Biostatistics
April 4, 2018
“Epigenetic clock: causes and consequences”

Job Dekker, PhD
Howard Hughes Medical Institute
Department of Biochemistry and Molecular Pharmacology
University of Massachusetts Medical School
Investigator
Professor and co-director, Program in Systems Biology
May 16, 2018
“Folding, unfolding and refolding of genomes”

Ernest Fraenkel
Professor
Department of Biological Engineering
Massachusetts Institute of Technology
June 13, 2018
TBD

2015-2016 Seminar Speaker Schedule

co-sponsored by the Translational Genomics Research Seminar Brigham Research Institute

Seminars in Molecular and Genomic Medicine (formerly known as Molecular Medicine Seminar Series - MMSS) received funds in 2013-2015 from Agilent, Illumina, and Merck

Jeremy Luban, MD
University of Massachusetts Medical School
Professor
February 14, 2018
Dendritic cell response to pathogens and tolerogens as a groovy model for understanding human transcriptional regulation

David Walt, PhD
Brigham and Women’s Hospital
Wyss Institute for Biologically Inspired Engineering
Howard Hughes Medical Institute
Professor
February 14, 2018
Single Molecule Arrays: From Fundamental Biochemistry to Diagnostics

Stuart Orkin, MD
Harvard Medical School, Howard Hughes Medical Institute
David G. Nathan Distinguished Professor of Pediatrics
Investigator
January 10, 2018
Genetics and epigenetics of the human fetal hemoglobin switch
and prospects for its direct manipulation

Tuuli Lappalainen, PhD
Assistant Investigator and Assistant Professor
New York Genome Center & Columbia University
December 13, 2017
Functional variation in the human genome: lessons from the transcriptome

Laurie Boyer, PhD
Massachusetts Institute of Technology
Irvin and Helen Sizer Career Development Associate Professor of Biology
November 8, 2017
Reprogramming a broken heart

Jason D. Buenrostro, PhD
Broad Institute of Harvard and Massachusetts Institute of Technology
Broad Institute Fellow
October 11, 2017
From ensembles to single-cells: A window into cis- and trans- epigenomic variability

Professor Harmen Bussemaker, PhD
Columbia University
Department of Biological Sciences
Department of Systems Biology
April 26, 2017
Accurate Quantification of Protein-DNA Recognition from Sparse Sequencing Data

Luca Giorgetti, PhD
Group Leader
Friedrich Miescher Institute (FMI)
for Biomedical Research
Basel, Switzerland
February 16, 2017
Structure vs Function: A quantitative analysis of chromosome structure and long-range transcriptional regulation in mammals

Heidi Mcbride, PhD
Canada Research Chair in Mitochondrial Cell Biology
Professor, McGill University
June 3, 2016
Uncovering the physiological role of mitochondrial SUMOylation

Olivier Pouquié, PhD
Brigham and Women's Hospital
Department of Genetics
April 6, 2016
Making muscle in vivo and in vitro

Levi Garraway, MD, PhD
Dana-Farber Cancer Institute
Department of Medical Oncology
March 30, 2016
From Genome Biology to Cancer Precision Medicine

Allon Moshe Klein, PhD
Harvard Medical School
February 24, 2016
Stochastic fate choice and single cell analysis of stem cell populations

Joseph Thornton, PhD
University of Chicago
December 9, 2015
TBD

Gordon L. Hager, PhD
Chief and Senior Investigator
Laboratory of Receptor Biology and Gene Expression
Center for Cancer Research
National Cancer Institute
November 18, 2015
A dynamic Equilibrium Model for Enhancer Function

Matthew Stephens, PhD
Professor, Department of Human Genetics and Department of Statistics
University of Chicago
October 21, 2015
Genetic association analysis of multiple phenotypes and/or multiple groups

Geoffrey S. Ginsburg, MD, PhD
Director, Center for Applied Genomics & Precision Medicine
Duke University School of Medicine
September 9, 2015
Novel Genomic Paradigms for Early Detection of Acute and Chronic Disease

Myles Brown, MD
Dana-Farber Cancer Institute
May 13, 2015
Genetics and Epigenetics of Hormone Dependent Cancers

Kiran Musunuru, MD, PhD
Harvard University Department of Stem Cell and Regenerative Biology
April 29, 2015
From genotype to phenotype to therapeutics at cardiovascular disease loci

Cynthia Morton, PhD
Brigham and Women’s Hospital/ Harvard Medical School
March 11, 2015
Looking Under the Lamppost: Genome Annotation through Sequencing Balanced

Feng Zhang, PhD
Broad Institute and Massachusetts Institute of Technology
January 21, 2015
Genome Engineering: Technologies and Applications

Bing Ren, PhD
University of California San Diego
November 19, 2014
More than beads on a string: Exploring Gene Regulation in the 3D genome

Angela DePace, PhD
Harvard Medical School
October 15, 2014
Shadow enhancers enable complex transcriptional circuit in Drosophila embryos

Jason M. Johnson, PhD
Associate Vice President
Merck
June 18, 2014
Data and information sciences in pharmaceutical research

Haiyuan Yu, PhD
Assistant Professor
Department of Biological Statistics and Computational Biology
Weill Institute for Cell and Molecular Biology
Cornell University
June 11, 2014
Understanding molecular mechanisms of human disease mutations through 3D protein network models

Ken Zaret, PhD
Joseph Leidy Professor in the Department of Cell and Developmental Biology
University of Pennsylvania School of Medicine
May 28, 2014
Mechanisms of Cell Programming and Reprogramming

Tian Xu, PhD
Professor of Genetics
Yale School of Medicine
May 21, 2014
Growth and Size Regulation in Development & Disease

Xiaole Shirley Liu, PhD
Professor, Biostatistics and Computational Biology
Dana-Farber Cancer Institute
May 14, 2014
Integrating High Throughput Data to Infer Function of Chromatin Regulator and LncRNAs in Cancer

Caroline Fox, MD
Associate Clinical Professor of Medicine
Brigham and Women's Hospital
Framingham Heart Study
April 16, 2014
Using Genomic Studies to Provide Insights into Kidney Function

Nicholas Katsanis, PhD
Director, Center for Human Disease Modeling
Professor of Cell Biology
Brumley Distinguished Professor of Pediatrics
Duke University
March 26, 2014
Modeling the Morbid Human Genome

Derrick Rossi, PhD
Assistant Professor of Stem Cell and Regenerative Biology
Children's Hospital, Boston
March 5, 2014
Reprogramming committed blood cells to induced hematopoietic stem cells with defined factors

Evan Rosen, MD, PhD
Associate Professor of Medicine
Harvard Medical School
Beth Israel Deaconess Medical Center
February 26, 2014
Epigenomic and transcriptional analysis of adipose biology

Vamsi K. Mootha, MD
Professor of Systems Biology
Massachusetts General Hospital
Harvard Medical School
January 22, 2014
Mitochondrial parts, pathways, and pathogenesis

Suzanne Gaudet, PhD
Assistant Professor of Genetics
Dana-Farber Cancer Institute
January 15, 2014
Leveraging cell-to-cell variability to understand signal transduction circuits

Keith Joung, MD, PhD
Associate Professor of Pathology
Massachusetts General Hospital
December 11, 2013
Targeted Genome and Epigenome Editing Using TALE and CRISPR-Cas Technologies

Jay Shendure, MD, PhD
Associate Professor of Genome Sciences
Department of Genome Sciences
University of Washington
February 8, 2012
Next-Generation Human Genetics

Didier Stainier, PhD
Professor, Department of Biochemistry & Biophysics
University of California, San Francisco
December 15, 2011
Development of Cardiac Form and Function in Zebrafish

Michel Georges, D.V.M., PhD
Professor
Unit of Animal Genomics GIGA-R & Faculty of Veterinary Medicine
University of Liege, Belgium
November 10, 2011
The long and winding road from correlation to causation in the genetics of human diseases: lessons from animal genetics

Yang Chai D.D.S., PhD
George and MaryLou Boone Professor
Director, Center for Craniofacial Molecular Biology
Associate Dean of Research
Ostrow School of Dentistry
University of Southern California
September 26, 2011
TGF-beta signaling mechanism in regulating craniofacial development and tissue regeneration

Robert Green, MD, M.P.H.
Professor
Boston University School of Medicine and Public Health
October 27, 2010
Translational Genomics and Health Outcomes: A New Research Discipline

Karen Avraham, PhD
Chair of the Department of Human Molecular Genetics and Biochemistry
Tel Aviv University School of Medicine
October 7, 2010
microRNA Regulation in the Inner Ear: Implications for Deafness