Laboratories and Research Projects

The departments and divisions at Brigham and Women's Hospital are reputed for their excellence in research. Housing both laboratory and clinical research initiatives, investigators in each department and division are focused on a variety of research issues both within and beyond the confines of the traditional outpatient department.

Should you like more information about a research team that is not linked below, contact and reference this page and the laboratory's name.

Anesthesiology, Perioperative and Pain Medicine (Department of)

Dermatology (Department of)

Emergency Medicine (Department of)

  • STRATUS Center for Medical Simulation, Charles Pozner, MD
  • Division of International Health and Humanitarian Programs, Michael Vanrooyen, MD, MPH; Stephanie Rosborough, MD, MPH; P. Gregg Greenough, MD, MPH; Hilarie Cranmer, MD, MPH; Kelli O’Laughlin, MD, MPH
  • Institute for International Emergency Medicine and Health, Mark A. Davis, MD; Kelli O’Laughlin, MD, MPH
  • National Emergency Airway Registry, Calvin A. Brown, MD; Daniel J. Pallin, MD, MPH
  • Principal Investigator and Coordinating Center for multi-center studies of child abuse detection, Daniel Lindberg, MD
  • Clinical and epidemiological research, with trials on community-associated methicillin-resistant Staphylococcus aureus, asthma, and other topics; and epidemiological studies on health information technology in emergency medicine, Daniel J. Pallin, MD, MPH
  • Clinical Research Program, Research Director: Guruprasad Jambaulikar, MBBS, MPH
  • Health Services and Clinical Research on Quality and Efficiency of Emergency Care, Jeremiah D. Schuur, MD, MHS
  • Division of Emergency Critical Care Medicine Research, Imoigele Aisiku, MD; Peter Hou, MD; Raghu Seethala, MD; Michael Billington, MD; Jason Cohen, MD
  • Disaster Preparedness and Hospital Surge Capacity, Richard Zane, MD
  • Policy relevant health services research focusing on longitudinal and cross sectional variation in cost and quality of care in emergency medicine. Michael Wilson, MD, PhD
  • Emergency Ultrasound Research Group, James Q. Hwang, MD; Elke Platz, MD; Heidi Kimberly, MD
  • Variation and guideline compliance in use of radiological studies for emergency care, Ali Raja, MD, MBA
  • Universal Screening for HIV Infection in the ER USHER, and Medical Education Research, Christian Arbelaez, MD, MPH
  • Pharmacoepidemiology and drug safety, Andrew T. McAfee, MD, MSc

Medicine (Department of)

Medicine: Division of Aging

Medicine: Division of Allergy and Clinical Immunology

Medicine: Division of Cardiovascular Medicine

  • Donald W. Reynolds Foundation Cardiovascular Clinical Research Center, Peter Libby, MD
  • Leducq TransAtlantic Network on Atherothrombosis Research, Peter Libby, MD
  • NMR Laboratory for Physiological Chemistry, Joanne Ingwall, PhD
  • Center for Cardiovascular Disease Prevention-Joint Program with Preventive Medicine, Paul M. Ridker, MD
  • Center for Clinical Biometrics and Harvard Clinical Research Institute, Laura Mauri, MD
  • Center for Interdisciplinary Cardiovascular Sciences, Masanori Aikawa, MD, PhD
  • Vascular Medicine Program, Mark Creager, MD
  • Arterial Dysfunction Program, Thomas Michel, MD, PhD
  • Heart Failure Clinical Research Network, Lynne Stevenson, MD
  • Vascular Medicine Research Group, James Liao, MD
  • Clinical Endpoints Center, Marc Pfeffer, MD and Scott Solomon, MD
  • Research and Education Program-PREP, Marc Pfeffer, MD
  • Vascular Profiling Laboratory-Ambulatory ECG/12-lead ECG Core Laboratory, Peter Stone, MD
  • Center for Arrhythmia Prevention, Christine Albert, MD

Medicine: Channing Laboratory

  • Bacteriology Section, Dennis Kasper, MD
  • Epidemiology Section, Frank Speizer, MD
  • Virology Section, Elliot Kieff, MD
  • Program in Biostatistics, Bernard Rosner, MD
  • Program in Environmental and Occupational Diseases, Respiratory Diseases, and Population Genetics, Scott Weiss, MD
  • Program in Pharmacoepidemiology and Infectious Disease Epidemiology, Richard Platt, MD
  • Chronic Disease Epidemiology Group, Meir Stampfer, MD, DrPH

Medicine: Division of Endocrinology, Diabetes and Hypertension

  • Aldosterone Research Group
  • Thyroid Section, Antonio Bianco, MD

Medicine: Division of Gastroenterology, Hepatology and Endoscopy

  • Blumberg Laboratory, Richard Blumberg, MD
  • Carey Laboratory, Martin Carey, MD, DSc
  • Cohen Laboratory, David Cohen, MD, PhD
  • Thompson Laboratory, Christopher Thompson, MD
  • Ukomadu Laboratory, Chinweike Ukomadu, MD, PhD
  • Zhu Laboratory, Zhenglun Zhu, MD

Medicine: Division of General Internal Medicine and Primary Care

Medicine: Division of Genetics

  • Cancer Genetics: Cichowski Lab, Karen Cichowski, PhD
  • Clinical Research and Clinical Trials: Leboulch Lab, Philippe Leboulch, MD
  • Computational Genetics: Bulyk Lab, Martha Bulyk, PhD; Sunyaev Lab, Shamil Sunyaev, PhD
  • Disease Oriented Research: Beier Lab, David Beier, MD, PhD; Cichowski Lab, Karen Cichowski, PhD; Maas Lab, Richard Maas, MD; Sunyaev Lab, Shamil Sunyaev, PhD
  • Gene Discovery and Gene Mapping: Beier Lab, David Beier, MD, PhD; Maas Lab, Richard Maas, MD
  • Gene Therapy: Leboulch Lab, Philippe Leboulch, MD
  • Genome Science: Bulyk Lab, Martha Bulyk, PhD; Sunyaev Lab, Shamil Sunyaev, PhD
  • Human Genetics: Maas Lab, Richard Maas, MD; Sunyaev Lab, Shamil Sunyaev, PhD
  • Medical and Population Genetics: Cichowski Lab, Karen Cichowski, PhD; Sunyaev Lab Shamil Sunyaev, PhD
  • Murine Molecular Genetics: Beier Lab, David Beier, MD, PhD; Cichowski Lab, Karen Cichowski, PhD; Maas Lab, Richard Maas, MD
  • Organogenesis and Development: Beier Lab, David Beier, MD, PhD; Maas Lab, Richard Maas, MD
  • Stem Cells and Regenerative Medicine: Maas Lab, Richard Maas, MD

Medicine: Division of Global Health Equity

  • CBPR to Refine an ART Adherence Intervention, Heidi Behforouz
  • Assessing mental health services needs and preferences in HIV/AIDS affected youth in Rwanda, Theresa Betancourt
  • Developing and piloting a quantitative behavioral assessment battery and a mental health intervention among HIV/AIDS affected youth, Theresa Betancourt
  • Adapting an evidence-based intervention for strengthening HIV/AIDS affected families, Theresa Betancourt
  • Epidemiology and outcomes of heart failure in Rwanda, Gene Bukhman
  • Assessing and Improving the Quality of Life of Cuban AIDS Patients, Arachu Castro
  • The Latin American and Caribbean Initiative for the Integration of Prenatal Care with the Testing and Treatment of HIV and Syphilis: a Comparative Study in Brazil, Colombia, Dominican Republic, Nicaragua, Paraguay, Uruguay, and Peru, Arachu Castro
  • Laboratory Turnaround Time in the Dominican Republic: Analysis of the Flow of Blood Specimens and Tests Results for HIV and Syphilis during Prenatal Care, Arachu Castro
  • Determining the temporal and spatial distribution of tuberculosis in Lima, Peru, Ted Cohen
  • MIDAS Center for Communicable Disease Dynamics, Ted Cohen
  • Prevalence, risk factors, and consequences of complex M. tuberculosis infections, Ted Cohen
  • Psychosocial intervention in HIV-affected children in Haiti, Mary Kay Smith Fawzi, Joia Mukherjee
  • Strengthening Medical Records and Technical Capacity in Rwanda through Mentorship and International Collaboration, Hamish Fraser
  • Managing Patient Data, Procurement, and Reporting Within Large-Scale Treatment Programs: The Potential of OpenMRS, Hamish Fraser
  • Evolution of OpenMRS from a Loosely Structured Collaborative Into a Formal Organizatio,n Hamish Fraser
  • Supporting the rollout of the OpenMRS in Rwanda, Hamish Fraser
  • Tailored nutrition and food security interventions in comprehensive HIV care, Louise Ivers
  • Identifying HIV and related stigma in rural Hait,i Louise Ivers
  • Non-governmental organizations and transnational technology transfer: Controlling drug-resistant tuberculosis in post-Soviet Russia, Salmaan Keshavjee
  • Overcoming barriers to effective treatment of multidrug-resistant tuberculosis, Salmaan Keshavjee, Sonya Shin
  • Exploring the role of community and social supports for patients receiving treatment for multi-drug resistant tuberculosis without direct observation of therapy, Salmaan Keshavjee
  • Health outcomes/cost of early vs. delayed ART in Haiti, Serena Koenig
  • Evaluations and Resources Inputs Research, Chunling Lu
  • Clinical, social and adherence outcomes for HIV positive children participating in a comprehensive HIV care and treatment program in rural Rwanda, Sara Stulac, Joia Mukherjee
  • Diarrheal disease, nutritional status, survival and adherence among formula fed infants of women living with HIV/AIDS, Sara Stulac, Joia Mukherjee
  • Epidemiology and transmission dynamics of MDR/XDR tuberculosis, Megan Murray
  • TB Drug Resistance Mutation Database, Megan Murray
  • Mono-resistance to INH and fluoroquinolones in South Africa, Megan Murray
  • Determinants of tuberculosis, Megan Murray
  • Interactions between Diabetes and tuberculosis, Megan Murray
  • Timing of ART in patients co-infected with HIV and TB in Rwanda, Megan Murray
  • Testing interventions of human generated occupational airborne infections, Ed Nardell
  • Computational Assisted Design for Engineering Upper Room Ultraviolet UV Air Disinfection, Ed Nardell
  • Inhaled Dry Powder Capreomycin - a Phase Ia Study, Ed Nardell
  • Inhaled Antimicrobials to Reduce MDR-TB Transmission to HIV-Infected Patients, Ed Nardell
  • Outcomes of 1041 patients receiving antiretroviral therapy in rural Rwanda under a model of accompaniment and high treatment support, Michael Rich
  • Evaluating and enhanced adherence support intervention for patients at risk of Antiretroviral treatment failure in Rural Rwanda, Michael Rich
  • Evaluating two models of ART delivery in rural Rwanda, Michael Rich
  • Evaluating adherence in patients receiving 2 models of ART care in rural Rwanda, Michael Rich
  • Strengthening and Studying Community-Based, Integrated Primary Health Care Systems in Rural Rwanda, Michael Rich
  • Implementation of rapid diagnostic methods for MDR-TB under program conditions, Sonya Shin
  • Integration of alcohol care into TB services, Sonya Shin
  • Improving diagnosis and treatment adherence among TB-HIV co-infected individuals, Sonya Shin
  • Effectiveness of alcohol interventions among TB patients in Tomsk Russia, Sonya Shin
  • Community-based outreach for Chronic Disease Management in Native American Populations, Sonya Shin
  • Community-based accompaniment with supervised antiretrovirals in Lima, Peru, Sonya Shin
  • Community-based detection of HIV-TB co-infection in an urban resource-poor setting, Sonya Shin

Medicine: Division of Hematology

Medicine: Division of Infectious Disease

  • Antiretroviral Therapeutics and Drug Resistance Daniel Kuritzkes, MD
  • HIV Clinical Research, Paul Sax, MD
  • HIV Vaccine Trials Unit, Lindsey Baden, MD
  • Clinical Epidemiology, Richard Platt, MD
  • Epstein-Barr Virus Pathogenesis, Elliott D. Kieff, MD, PhD
  • Global Health & Equity, Paul Farmer, MD
  • Streptococcus and Bacterial Pathogenesis, Dennis Kasper, MD
  • Transplantation, Lindsey Baden, MD
  • Tropical Medicine & Parasitology, James H. Maguire, MD, MPH
  • Tuberculosis, Eric Rubin, MD
  • International AIDS Research, Shahin Lockman, MD
  • Vaccine Development Immunocompromised Host Research, Lindsey Baden, MD and Raphael Dolin, MD
  • WHONET Antimicrobial Surveillance Research Group, Thomas O'Brien, MD and John Stelling, MD

Medicine: Center for Personalized Genetic Medicine

Medicine: Division of Pharmacoepidemiology

  • BWH DEcIDE Center, Sebastian Schneeweiss, MD

Medicine: Division of Preventive Medicine

Medicine: Division of Pulmonary and Critical Care Medicine

  • Asthma
  • Chronic Obstructive Pulmonary Disease COPD
  • Churg Strauss Syndrome CSS
  • Host Defense/Immunologic
  • Interstitial Lung Disease ILD
  • Lymphangioleiomyomatosis LAM
  • Lung Development
  • Lung Injury/Sepsis
  • Pulmonary Hypertension
  • Stem Cell/Regenerative Medicine

Medicine: Renal Division

Medicine: Division of Rheumatology, Inflammation and Immunity

Medicine: Division of Sleep Medicine

  • Clinical Sleep Disorders Program
  • Sleep Disorders Research Program
  • Sleep, Aging and Circadian Rythym Disorders, PPG program project, Charles A. Czeisler, MD, PhD
  • Training in Sleep, Circadian & Respiratory Neurobiology T-32 Training Grant, Charles A. Czeisler, MD, PhD
  • National Space Biomedical Research Institute, Drs. Czeisler, Klerman and Lockley

Medicine: Division of Translational Medicine

  • Stossel Laboratory, Thomas P. Stossel, MD
  • Hartwig Laboratory, John H. Hartwig, PhD
  • Kwiatkowski Laboratory, David J. Kwiatkowski, MD, PhD
  • Dabora Laboratory, Sandra L. Dabora, MD, PhD
  • Hoffmeister Laboratory, Karin M. Hoffmeister, MD

Neurology (Department of)

Neurology: Division of Basic Neuroscience Research, Dennis J. Selkoe, MD

Neurology: Division of Cognitive and Behavioral Neurology, Kirk Daffner, MD

Neurology: Division of Neuro-Critical Care, Brad Molyneaux, MD, PhD

Neurology: Division of Epilepsy and Sleep Neurology, Barbara Dworetzky, MD

  • Edward B. Bromfield Comprehensive Epilepsy Program, Barbara Dworetzky, MD

Neurology: Division of Headache and Pain, Elizabeth Loder, MD

Neurology: Division of General Neurology, Thomas Walshe, MD

Neurology: Division of Movement Disorders, Vikram Khurana, MD, PhD

Neurology: Division of Multiple Sclerosis and Neuro-Immunology, Howard L. Weiner, MD

Neurology: Division of Neuromuscular Disease, Anthony Amato, MD

Neurology: Division of Neuro-Ophthalmology, Don Bienfang, MD

Neurology: Division of Neuro-Oncology, Patrick Y. Wen, MD

Neurology: Division of Stroke and Cerebrovascular, Steven Feske, MD

Neurology: Women’s Neurology Program

Neurosurgery (Department of)

Obstetrics and Gynecology (Department of)

Orthopaedic Surgery (Department of)

Pathology (Department of)

Pathology - Vascular Biology Investigators:

Pulmonary Pathobiology Investigators:

Pathology - Immunology Investigators:

Pathology - Molecular Oncology Investigators:

Neuropathology Investigators:

Cardiac Pathology Investigators:

Women's and Perinatal Pathology Division:

Pathology - Skin Diseases Investigators:

Pathology - Genetic Basis of Inherited Disorders Investigators:

Surgical Pathology Investigators:

Pediatrics (Department of)

  • Center for Clinical and Epidemiological Research, Ellice S. Lieberman, MD, DrPH
  • Thorn 10, Helen Christou, MD
  • Thorn 10, Sule Cataltepe, MD
  • Thorn 10, Mark Perrella, MD
  • Karp Research Building, Paul Lerou, MD
  • Channing Lab, Karen Puopolo, MD
  • GCRC, Linda Van Marter, MD
  • CWN6, Richard Parad, MD
  • CWN6, Robert Insoft, MD
  • CWN6, Steven Ringer, MD, PhD
  • CWN6, Jennifer Cohen, MD
  • CWN6, Stella Kourembanas

Physical Medicine and Rehabilitation (Department of)

Psychiatry (Department of)

  • Study of Adult Development, George Vaillant, MD, Robert Waldinger, MD
  • Health Aging and Health Disparities, Sue Levkoff, ScD
  • Health E-Technologies, David Ahern, PhD
  • Psychiatry Neuroimaging Laboratory (PNL), Martha Shenton, PhD
  • Hypochondriasis Research, Arthur Barsky, MD
  • Women's Health and Substance Abuse, Grace Chang, MD
  • Brain region specific Oxidative stress in Autism, Elizabeth Sadjel-Sulkowska, ScD
  • Latina Diabetics and Body Image, Patricia Weitzman, PhD
  • Culturally and Clinical Sensitive Depression Instrument, Francis Yang, PhD
  • Fronto-Temporal Connectivity, Marek Kubicki, MD, PhD

Radiation Oncology (Department of)

  • BROADBAND (BWH Radiation Oncology All-Department Biorepository to Accelerate New Discoveries), David Kozono, MD, PhD
  • Cytogenic Diagnostic Facility, Alan D. D'Andrea, MD
  • DNA Research Laboratory Alan, D. D'Andrea, MD
  • Dana-Farber Center for Medical Countermeasures Against Radiation, Alan D. D'Andrea, MD

Radiation Oncology: Division of Genomic Stability

Radiation Oncology: Division of Medical Physics and Biophysics G. Mike Makrigiorgos, PhD

Radiology (Department of)

Surgery (Department of)

Surgery: Division of Cardiac Surgery

Surgery: Division of General and Gastrointestinal Surgery

Surgery: Division of Ophthalmology

Surgery: Division of Oral Medicine & Dentistry

  • Laboratory of Nathaniel S. Treister, DMD
  • Laboratory of Sook-bin Woo, DMD
  • Laboratory of Stephen Sonis, DMD

Surgery: Division of Otolaryngology

Surgery: Division of Plastic Surgery

Surgery: Division of Thoracic Surgery

Surgery: Division of Transplant Surgery

Surgery: Division of Trauma, Burn, and Critical Care

Surgery: Gillian Reny Stepping Strong Center for Trauma Innovation

Urology (Department of)

Women's Health

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