General and gastrointestinal surgeons at Brigham and Women’s Hospital are renowned scientific researchers, who are involved in a range of surgical and multi-modality, disease-specific clinical research. Research projects have resulted in revolutionary advances in surgery, such as modern intravenous (IV) therapy, modern blood banking equipment and optimal nutritional treatment for burn surgery patients.
Research in general and gastrointestinal surgery involves interdisciplinary discussion and collaboration among researchers at the Brigham and other scientists in the Boston area, throughout the United States and around the world. Together, we have built an integrated research effort among multiple disciplines each contributing to surgical innovations.
Select patients have the opportunity to participate in investigational clinical trials that study the safety and effectiveness of new treatment approaches for specific diseases. Cancer patients have direct access to the latest research-based treatments and clinical trials through our role in the Dana-Farber/Harvard Cancer Center (DF/HCC), a National Cancer Institute-funded consortium comprised of seven member institutions: Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Harvard T.H. Chan School of Public Health and Massachusetts General Hospital.
Research Study Examples
Research projects, including clinical trials focus on:
Liver and biliary duct cancer
New targeted cancer treatments using novel biologic drugs
Tissue analysis and typing to develop biomarkers for prognosis and diagnosis in cancer
Investigating new devices to aid in treatment, localization and tumor excision
Protocols to reduce postoperative stay and promote recovery
Quality of life studies aimed to improve lifestyle and reduce morbidities before and after surgery
New, more precise surgical approaches using the AMIGO suite
Characterization of the tumor genetic structure and function with emphasis on developing new therapies
Examining the physiological regulation of the intestinal sodium transporter SGLT1 in health and disease to help develop novel therapeutic approaches for altering intestinal absorptive capacity of glucose in disease states such as obesity and diabetes