Psychogenic non-epileptic seizures (PNES): Clinical characterization and predictors of outcome
An existing barrier to care for patients with PNES is the lack of adequate multidisciplinary care involving neurologists, psychiatrists, and psychologists. We propose to identify characteristics of the populations of post-monitored PNES patients to determine predictors of adherence, and clinical improvement.
Functional and structural biomarkers of psychogenic non-epileptic seizures (PNES)
To examine frontolimbic functional activation patterns and connectivity differences in patients with PNES compared to healthy control subjects; To examine interactions between right parietal-temporal and premotor regions as a function of dissociation in patients with PNES; To examine frontolimbic, right parietal-temporal, and premotor volumetric differences in patients with PNES compared to healthy control subjects.
BWH Role: Dr. David Perez, Neurology-Psychiatry resident, Principal Investigator.