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x0x0x0x0x0x01Justix1dcationfortheUseofStatinsinPrimaryPreventionAnInterventionTrialEvaluatingRosuvastatinRESEARCHOURSTRENGTHSBWHhasalonghistoryofleadingtheworldininnovativeresearchandinbringingsciencetothediagnosisandtreatmentofillness.ResearchandinnovationarecorevaluesofBWFx14wheresciencelearningandclinicalcareintersecttobenex0tourpatientsandtheirfamilies.BWFhasmorethan3700researchersphysicianscientistsnursesandclinicalandresearchfellowsnearly1000principalinvestigatorsandapproximately2800professionalandtechnicalstaffin42researchlocations.In2005BWHestablishedtheBiomedicalResearchInstituteBRIwhichfostersgroundbreakinginterdepartmentalandinterdisciplinaryresearchwithinthehospitalx19sresearchcommunity.TheBRIincludeseightdisease-focusedresearchcentersandx0veresource-andtechnology-basedprogramsandenablesourdiversecommunityofcliniciansandscientiststocommunicatemoreeffectivelyprovidingnumerousopportunitiesforthemtocollaborateonresearchaimedatcuringtreatingandpreventingahostofhumandiseasesandconditions.BWFx19ssubstantialcommitmenttoresearchisrex1ectedinthenumberofimportantdiscoveriesandinnovationsthesizeandscopeofourresearchportfolioourvolumeofscientix0cpublicationsandsupportfortheBRI.BWHishometoanumberoftheworldx19sbest-knownprospectivecohortstudiese.g.Nursesx19HealthStudyPhysiciansx19HealthStudyWomenx19sHealthStudyWomenx19sHealthInitiativeandhasmademanypivotaldiscoveriesoverthedecades.SomeexamplesofthemanypioneeringdiscoveriesstudiesandinnovationsincludeTheJUPITER1trialwhichidentix0edhigh-sensitivityC-reactiveproteinhsCRPasabiomarkerforriskofcardiovasculardiseaseanddemonstratedthatloweringhsCRPandLDLcholesterolreducedtheriskforacardiovasculareventby44percentIdentix0cationofgeneticriskfactorsthatcontributetorheumatoidarthritisDevelopmentofnanoparticlesasinnovativetargeteddrugdeliverysystemsPioneeringvitaminDstudiessuchastheVITaminDandOmegA-3TriaLVITALinvestigatingwhethervitaminD3oromega-3fattyacidsreducetheriskfordevelopingcancerheartdiseaseandstrokex1cAMIGOx1dtheadvancedmulti-modalimage-guidedoperatingroomconsistingofthreesterileprocedureroomsthathousesreal-timeimagingmodalitieslikeX-rayx1uoroscopyandultrasoundaswellascross-sectionaldigitalimagingsystemslikeCThigh-x0eldstrengthMRIandhigh-resolutionPETTheOurGenesOurHealthOurCommunityprojectwhichisstudyingtheinx1uenceofgenesenvironmentandlifestyleonhumanhealthinordertodevelopbetterwaystopreventandtreatdisease