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Bohdan Pomahac, MD, is the Principal Investigator for this grant. In addition to leading the face transplantation project at Brigham and Women’s Hospital, Dr. Pomahac is the Director of the BWH Burn Center and specializes in facial reconstructive procedures. His research is focused on wound healing, and he has an expertise in gene therapy as well as solving complex wound problems requiring free tissue transfer. He will be the overall supervisor of the project and will be responsible for the overall design, patient confidentiality, supervising the personnel and budget, preparing reports and overseeing the writing of manuscripts and protocols.
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Julian Joseph Pribaz, MD, Co-Investigator, Plastic Surgery, is a Professor of Surgery at Harvard Medical School. He specializes in complex reconstructive surgery, including that of the head and neck. He participated in the first face transplant performed at BWH in April 2009. His clinical and research interests include complex microsurgery of the head and neck, tissue neovascularization and prefabrication, facial artery musculomucosal flap (FAMM), submental flap, and free flap nasal reconstruction. Dr. Pribaz is considered one of the world leaders in facial reconstruction and has received numerous awards, honors and visiting professorships.
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Elof Eriksson, MD, PhD is the Chief of Plastic Surgery at Brigham and Women’s Hospital. His research in the laboratory for Tissue Repair and Gene Therapy broadly aims at creating better treatment for both acute and chronic wounds. The overall objective of his research program is to gain a better understanding of the molecular and cellular effects and interactions on wound repair in normal and impaired wounds.
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Dennis Paul Orgill, MD, PhD is the Associate Chief of Plastic Surgery at Brigham and Women’s Hospital in Boston. He is a Professor of Surgery at Harvard Medical School and serves as the Assistant Program Director of the Combined Harvard Plastic Surgery Residency Program. He received his medical degree from Harvard Medical School and later earned a PhD from MIT in Medical Engineering. He is well recognized for his abilities as a reconstructive plastic surgeon specializing in complex reconstructive procedures for cancer, trauma and burn patients. Dr. Orgill helped develop artificial skin for burn victims and has an active laboratory that studies and develops improved technologies in wound healing and tissue engineering.
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Matthew J. Carty, MD, Co-Investigator, Plastic Surgery, specializes in complex reconstructive surgery of the breast and hand. He specializes in microsurgical approaches, including the DIEP, SIEA and SGAP flaps for breast reconstruction following oncologic resection, as well as complicated flaps and tendon transfers for limb reconstruction following traumatic injury.
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Stephanie A. Caterson, MD, Co-Investigator, Plastic Surgery, completed her medical school training and general surgery residency at Jefferson Medical School in Philadelphia, PA. She went on to complete her plastic surgery residency at the Lahey Clinic in Boson, MA, followed by a Harvard fellowship in Breast Reconstruction and Microsurgery. Dr. Caterson specializes in breast reconstruction and is the director of the Microsurgical Breast Program at Brigham and Women’s Hospital.
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Edward J. Caterson, MD, PhD, Co-Investigator, Plastic Surgery, completed his Harvard Combined Plastic Surgery Residency in 2009, and a fellowship in craniofacial surgery at New York University Medical Center in 2010. His clinical interests are craniofacial surgery, craniofacial trauma, advanced cutaneous malignancy, and complementing the Brigham and Women's Hospital composite tissue transplantation research efforts with tissue engineering and regenerative medicine initiatives.
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Christian Edward Sampson, MD, Co-Investigator, Plastic Surgery, is an Assistant Professor of Surgery at Harvard Medical School. He received his medical degree from Boston University School of Medicine. Dr. Sampson specializes in complex hand and microsurgery, including tendon transfers, nerve repairs and vascular conditions. His research interests include Botulinum A Toxin as a means of therapeutic management of digital ischemia and Raynaud’s Disease. He is a co-investigator for this grant and participated in the first face transplant at Brigham and Women’s Hospital.
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Yoon Sun Chun, MD, Co-Investigator, Plastic Surgery, is a board-certified plastic surgeon specializing in reconstructive surgery. She received her medical degree from The Johns Hopkins School of Medicine and plastic surgery training from The Harvard Plastic Surgery Residency Program. As the Director of Reconstructive and Aesthetic Breast Surgery at Faulkner Hospital, her specific areas of expertise include oncologic reconstruction, reconstructive and aesthetic breast surgery, and clinical outcomes research. Her practice philosophy involves highly individualized patient evaluation and surgical design with an emphasis on clear communication of various treatment options.
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Donald J. Annino, Jr., MD, DMD, Co-Investigator, ENT
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Stefan G. Tullius, MD, PhD - is the Chief of Transplant Surgery at Brigham & Women’s Hospital. His research career in transplantation immunology covers a period of more than 15 years. His work on chronic graft rejection has contributed greatly to an improved understanding of the pathophysiology of long-term graft failure. His more recent research interests include individualized immunosuppression and the investigation of basic mechanisms of clinically relevant aspects in organ transplantation, focusing on novel routes for the improvement of organ quality. To better understand the potential of improving organ quality, he has developed relevant clinical models to study the effects of pulsatile perfusion on the expression of protective endothelial genes. He has also explored the expression of microRNAs and their capacity to regulate injury and repair in the context of ischemia and reperfusion injury. As an increasing number of older organs are transplanted in older patients, he has studied modifications of the immune response related to increasing age. He has shown through large-volume clinical data that increasing recipient age is associated with improved transplant survival and in experimental models he has shown an ameliorated immune response in older animals receiving organ transplants.
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Sayeed Khan Malek, MD, Co-Investigator, Transplant Surgery, is the Clinical Director of Transplant Surgery at Brigham and Women’s Hospital. He has done extensive research in renal transplant, with a focus on the immune response in transplant patients.
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Anil K. Chandraker, MB, CHB, Co-Investigator, Transplant Nephrology, is the Director of Renal Transplant Medicine for Brigham and Women’s Hospital. The major focus of his laboratory research is on the role of the T cell in chronic allograft rejection. His clinical research focuses on clinical problems that affect transplant patients.
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Edgar Louis Milford, MD, Co-Investigator, Transplant Nephrology, is a collaborator on this grant and is the Director of the Tissue Typing Laboratory. He has significant expertise with tissue typing in transplant patients.
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Srinivasan Mukundan, Jr., MD, PhD, Co-Investigator, Radiology, is the Section Head of Neuroradiology. He is also Co-Director of Clinical Functional Magnetic Resonance Imaging (fMRI).
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Frank John Rybicki, MD, PhD, Co-Investigator, Radiology, is the Director of the Applied Imaging Science Laboratory, Cardiac CT and Vascular CT/MRI. The mission of his research is to develop and test the next generation of magnetic resonance and computed tomography methods. He will monitor chronic rejection as evidenced by arterial wall hyperplasia.
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Francisco Marty, MD, Co-Investigator, Infectious Disease, is a collaborator on this grant and is an Assistant Professor of Infectious Disease at Harvard Medical School. His area of expertise is the study of infections in transplant patients.
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Thomas Edrich, MD, Co-Investigator, Anesthesia, holds an appointment at Harvard/Brigham and Women's Hospital. As an anesthesiologist and intensivist, he attends in the surgical, thoracic and cardiac intensive care units. In the operating room, he serves as an anesthesia liaison to the Transplant Surgery division. He coordinates the perioperative anesthesia management for the team performing facial transplantation. His research interests include pharmacokinetic modeling and airway pressure monitoring.
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Alexandra Golby, MD, Co-Investigator, Neurosurgery, is an Associate Surgeon at Brigham and Women’s Hospital in the Department of Neurosurgery, Director of Image-Guided Neurosurgery, and Assistant Professor of Surgery at Harvard Medical School. She received her BA from Yale University in 1989 and her MD from Stanford University in 1995. She completed her Neurosurgical training at Stanford University Medical Center and as the Chief Resident at BWH in 2002. Her research involves the application of brain mapping techniques to neurosurgical patients as well as neuroscientific investigations into the brain basis of cognition. The Golby lab uses multiple functional brain mapping techniques (functional MRI, diffusion tensor imaging, and intracranial EEG) to better understand the cognitive physiology of memory and other higher cognitive functions.
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Ericka Bueno, PhD, Co-investigator, Plastic Surgery Transplantation, acts as Scientific Director of the face, hand, and leg transplantation programs, providing liaison between all co-investigators and managing all aspects of the scientific portions of these studies. Dr. Bueno received her doctorate degree in Chemical Engineering from Northeastern University, with a thesis in orthopaedic tissue engineering. She completed a research fellowship at the Department of Orthopaedic Surgery at Brigham and Women’s Hospital prior to joining the face and hand transplantation teams.
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Laura Garren, OTR/L,works as a Senior Occupational Therapist in the Department of Rehabilitation Services. She graduated in 2002 from Quinnipiac University and joined the staff at Brigham and Women’s Hospital Rehabilitation Services in 2005. Laura is the primary Occupational Therapist for the Burn Service and Facial Transplant Team. She will manage the occupational therapy treatment for the face and hand transplant patients while they are admitted to Brigham and Women's Hospital.
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Melanie Parker, PT, is a Physical Therapy Clinical Specialist. She received her doctorate of physical therapy from Massachusetts General Hospital Institute of Health Professions and is board certified in neurologic physical therapy. She currently serves as the lead physical therapist for the Burn Center and the Division of Plastic Surgery.
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