Clinical Studies of Heart Failure Dr. Lynne W. Stevenson's investigation focuses on the elucidation of principles for the therapy of patients with heart failure. Current areas of research in this population include:
Impact of hemodynamically-guided therapy on outcomes
Reflex integration of heart rate, respiration, and blood pressure
Effect of therapy on endothelial regulation of blood flow and optimal distribution of the limited hearts for cardiac transplantation
Neuroendocrine responses to loading conditions
Contribution of heart rate responses to chronic ventricular function
Oxygen kinetics of submaximal exercise
Stevenson LW, Warner SL, Steimle AE, et al. The impending crisis awaiting cardiac transplantation: modeling a solution based on selection. Circulation 89:450-457; 1994.
Stevenson LW, Couper G, Natterson BJ, et al. Target heart failure populations for newer therapies. Circulation (In press.)