Department of Surgery Research

Dr. Steven Mentzer's Research Videos

 

Video 2

3D structured illumination confocal reconstruction of a small area of the colon microcirculation.  The vessels were labeled with a green lipophilic fluorescent dye (DiO), acquired in a “whole mount” of the colon wall, then reconstructed into a 3D model using rendering software.

Region of the colon mucosa “mapped” by high resolution images of the mucosal crypts (blue) and microcirculation (green). The use of “mosiacized” images of the mucosa allows for the investigation of spatial patterns and the application of spatial statistics.

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Video 4

Intravital microscopy recording of fluorescent nanoparticles in acute colitis.  Integrated flow patterns from a much longer videos sequence is summarized by the orange overlay.  The gaps in the honeycomb network represents occluded vessel segments. Because of the large file size of the experimental data, the video shown here is “looped” for presentation purposes.

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Video 5

A microchannel fabricated with a “column” or “pillar” within the lumen.  The microchannels are 100um in diameter and can be produced in a variety of geometries.  In this video sequence, the flow paths of fluorescent particles are being studied.

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