The Schuster Family Transplantation Research Center (TRC) is a multifaceted group of clinicians and investigators that strives to dramatically improve outcomes for recipients of transplanted organs. We emphasize the importance of translational research, starting in the clinic with recognition of the life-long challenges that recipients face - before, during and after transplant surgery. In the laboratory, researchers probe complex processes such as allorecognition and rejection, improvements in surgical technique and drug development. This bedside-to-bench philosophy lies at the core of the Center’s values.
Anil Chandraker, MD Interim Director Associate Professor Defining T cell phenotypes of transplant recipients with stable and deteriorating renal function Development of anti-HLA antibodies after transplantation; effectiveness of quinolone antibiotics against polyoma virus in renal transplant recipients
Reza Abdi, MD Assistant Professor Roles of chemokines in the pathogenesis of allograft rejection; role of specific chemokines and their receptors in islet allograft rejection
Jamil Azzi, MD Instructor Exploring novel therapeutic strategies that preferentially promote immune regulation and induce tolerance to self and alloantigens
Nader Najafian, MD Assistant Professor Role of costimulatory molecules in autoimmunity and in allograft rejection/tolerance
Leonardo Riella, MD, PhD Instructor Mechanisms of chronic rejection and novel potentials pathways important for transplantation tolerance, such as the Notch pathway and negative costimulatory pathways (PD1:PDL1)
Mohamed Sayegh, MD Professor Mechanisms of allograft rejection and transplantation tolerance