Extensive research efforts at the Stroke and Cerebrovascular Center at Brigham and Women’s Hospital include many NIH-funded studies designed to lead to new therapies for stroke and cerebrovascular disease.
Researchers at the Center are examining:
Mechanisms of neuroapoptosis, or programmed cell death, in the evolution of stroke
Use of neuroprotective agents to minimize cell death in stroke, traumatic brain injury, and cerebrovascular disease
Markers and mechanisms of injury in stroke
Micro- and cerebrovascular pathophysiology, molecular pathology, and therapeutic ramification of stroke
Endovascular devices and approaches to acute ischemic stroke treatment
Transcranial Doppler ultrasound in the study of hemodynamic pathophysiology
Genetic basis for cerebrovascular disorders, including aneurysms
BWH is participating site in the National Institute of Neurological Disorders and Stroke (NINDS) StrokeNET Clinical Trials Network. Through this network, physicians at BWH enroll patients into multiple advanced clinical trials aimed at stroke prevention, acute treatment, and recovery.