Extensive research efforts at the Stroke and Cerebrovascular Center at Brigham and Women's Hospital include many NIH-funded studies designed to lead to new therapies for stroke and cerebrovascular disease.
Researchers at the Center are examining:
- Mechanisms of neuroapoptosis, or programmed cell death, in the evolution of stroke
- Use of neuroprotective agents to minimize cell death in stroke, traumatic brain injury, and cerebrovascular disease
- Markers and mechanisms of injury in stroke
- Micro- and cerebrovascular pathophysiology, molecular pathology, and therapeutic ramification of stroke
- Endovascular devices and approaches to acute ischemic stroke treatment
- Transcranial Doppler ultrasound in the study of hemodynamic pathophysiology
- Genetic basis for cerebrovascular disorders, including aneurysms
BWH is participating site in the National Institute of Neurological Disorders and Stroke (NINDS) StrokeNET Clinical Trials Network. Through this network, physicians at BWH enroll patients into multiple advanced clinical trials aimed at stroke prevention, acute treatment, and recovery.