Centers of Excellence

Orthopaedic & Arthritis Center

Orthopaedic and Arthritis Center Clinical Trials

Brigham and Women’s Hospital (BWH) is a world leader in clinical research, a critical aspect of improving orthopaedic and joint disease care. Brigham and Women's Hospital collaborates in clinical trials as a member in the multi-institutional Dana-Farber/Harvard Cancer Center (DF/HCC) and Clinical Trials @ Partners HealthCare.

A clinical trial is a carefully controlled study of the safety and effectiveness of a medical treatment, strategy, device, or other intervention for humans. By participating in a clinical trial, which is strictly voluntary, a patient may help researchers discover a new life-saving medication or surgical procedure.

Partners HealthCare provides an online directory of all clinical trials open to new participants at BWH and other Partners HealthCare institutions. Below is a listing of open research trials focused on orthopaedic and joint diseases and conditions. Click on a title of interest to be directed to study details and enrollment information.

Clinical Trial Categories:

Bones, Joints and Muscles

Fitness and Exercise

Injuries and Wounds

Surgery and Rehabilitation

Trials by Topics:


Back Pain

Bone Density

Connective Tissue Disorders

Exercise and Physical Fitness

Hip Injuries and Disorders

Joint Disorders

Knee Injuries and Disorders

Knee Replacement

Limb Loss


Neck Injuries and Disorders



Psoriatic Arthritis

Raynaud’s Disease

Rheumatoid Arthritis


Spinal Cord Injuries

Sports Fitness

Sports Injuries

Sarcoma Clinical Trials

A sarcoma is a tumor that forms in connective tissue -- bones, muscles, tendons, cartilage, nerves, fat, and blood vessels. There are two main kinds of sarcoma: soft tissue sarcoma and bone sarcoma (osteosarcoma).


For over a century, a leader in patient care, medical education and research, with expertise in virtually every specialty of medicine and surgery.

About BWH