Orthopaedic and Arthritis Center Clinical Trials

Brigham and Women’s Hospital (BWH) is a world leader in clinical research, a critical aspect of improving orthopaedic and joint disease care. Brigham and Women's Hospital collaborates in clinical trials as a member in the multi-institutional Dana-Farber/Harvard Cancer Center (DF/HCC) and Clinical Trials at Mass General Brigham.

A clinical trial is a carefully controlled study of the safety and effectiveness of a medical treatment, strategy, device, or other intervention for humans. By participating in a clinical trial, which is strictly voluntary, a patient may help researchers discover a new life-saving medication or surgical procedure.

Mass General Brigham provides an online directory of all clinical trials open to new participants at BWH and other Mass General Brigham institutions. Below is a listing of open research trials focused on orthopaedic and joint diseases and conditions. Click on a title of interest to be directed to study details and enrollment information.

Clinical Trial Categories

• Bones, Joints and Muscles
• Fitness and Exercise
• Injuries and Wounds
• Surgery and Rehabilitation

Trials by Topics

• Arthritis
• Back Pain
• Bone Density
• Connective Tissue Disorders
• Exercise and Physical Fitness
• Hip Injuries and Disorders
• Joint Disorders
• Knee Injuries and Disorders
• Knee Replacement
• Limb Loss
• Lupus
• Neck Injuries and Disorders
• Osteoarthritis
• Osteoporosis
• Psoriatic Arthritis
• Raynaud’s Disease
• Rheumatoid Arthritis
• Scleroderma
• Spinal Cord Injuries
• Sports Fitness
• Sports Injuries

Sarcoma Clinical Trials

A sarcoma is a tumor that forms in connective tissue -- bones, muscles, tendons, cartilage, nerves, fat, and blood vessels. There are two main kinds of sarcoma: soft tissue sarcoma and bone sarcoma (osteosarcoma).

• View open sarcoma trials at DF/HCC.