The Center for Neurological imaging (CNI) is a joint venture between the Departments of Neurology and Radiology at Brigham and Women's Hospital, and is the imaging arm of the BWH/MGH Multiple Sclerosis Center. The CNI became operational in the fall of 2000 and consists of a magnetic resonance imaging (MRI) facility and an image analysis laboratory (IAL). The MRI facility includes a dedicated 1.5Tesla MR scanner, which is adjacent to the Radiology Department's 3T system. Together these two state-of-the-art imaging systems provide outstanding capability for imaging the central nervous system (CNS). The image analysis laboratory is a powerful computer facility dedicated to the quantification and visualization of CNS structures.