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William (Stan) Anderson, MD, PhD

William (Stan) Anderson, MD,PhD

Director, Epilepsy Research
Associate Surgeon
Department of Neurosurgery, Brigham and Women's Hospital
Instructor of Surgery (Neurosurgery)
Harvard Medical School

The Anderson laboratory focuses on computational modeling of epileptic activity in the brain, with simulations ranging from simple interconnected single compartment cells, to elaborate multicompartment cellular representations with dendritic, somal, and axonal compartments. The goal of this work is to understand the time and spatial evolution of seizures and effects of therapeutic interventions like drug delivery and electrical stimulation. Additionally, Dr. Anderson studies the temporal nature of the electrophysiology of memory encoding in the mesial temporal lobe through electrical stimulation disruption studies in invasively monitored epilepsy patients. Recordings made during deep brain stimulator implantation are also used to explore motor imagery related activity in subcortical structures as a way to explore the brain’s motor planning system. Dr. Anderson works closely with Dr. Gabriel Kreiman at Children’s Hospital, Boston.