Austen Group Publications

Ago H, Kanaoka Y, Irikura D, Lam BK, Shimamura T, Austen KF, Miyano M.  Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.  Nature 2007; 448:609-12.

Abonia JP, Hallgren J, Jones T, Shi R, Xu Y, Koni P, Flavell RA, Boyce JA, Austen KF, Gurish MF.  Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung.  Blood 2006; 108:1588-94.

Chen M, Lam BK, Kanaoka Y, Nigrovic PA, Audoly LP, Austen KF, Lee DM.  Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.  J Exp Med 2006; 203:837-42.

Arinobu Y, Iwasaki H, Gurish MF, Mizuno S, Shigematsu H, Ozawa H, Tenen DG, Austen KF, Akashi K.  Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.  Proc Natl Acad Sci USA 2005; 102:18105-10.

Abonia JP, Friend DS, Austen Jr WG, Moore Jr FD, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF.  Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle.  J Immunol 2005; 174: 7285-91.

Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y.  Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice.  J Biol Chem 2004; 44:46129-34.

Schmidt-Krey I, Kanaoka Y, Mills DJ, Irikura D, Haase W, Lam BK, Austen KF, Kühlbrandt W.  Human leukotriene C4 synthase at 4.5 Å resolution in projection.  Structure 2004; 12:2009-14.

Zhou JS, Friend DS, Feldweg AM, Daheshia M, Li L, Austen KF, Katz HR.  Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: Evidence for an important role for gp49B1 expression on neutrophils.  J Exp Med 2003; 198:1243-51.