Clinical Research Tools

Cardiovascular Disease (CVD) Risk Calculator

The rheumatoid arthritis CVD risk calculator (Extended Risk Score – Rheumatoid Arthritis, ERS-RA) was developed and validated by Dr. Daniel Solomon and colleagues using data from CORRONA.  It is not meant as a substitute for clinical judgment.  Patients and providers can use it as a tool to predict cardiovascular risk in patients with rheumatoid arthritis.  You can find the risk calculator here.

Connective tissue disease screening questionnaire (CSQ) 

The CSQ was developed by Dr. Elizabeth Karlson and others in the BWH Section of Clinical Sciences as a validated technique for screening individuals in the general population for presence of a connective tissue diseases (CTD) including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), scleroderma, polymyositis, dermatomyositis, mixed connective tissue disease (MCTD) and Sjogren’s syndrome. Because CTD are uncommon in the general population, the CSQ provides an effective screen to identify subjects with CTD for further study and has been applied to several population based studies.  Click here for more information on the CSQ.  To obtain the CSQ for your studies, please contact Anne Donnelly.

Rheumatoid Arthritis (RA) Severity

This paper from researchers at BWH and the Veteran’s Administration Health System defines an index for using administrative claims data for estimating RA severity.  The claims-based index for RA severity (CIRAS) has been used in multiple papers and the component codes are available here.

Rheumatoid Arthritis Validation 

Many investigators want to use health care utilization databases for RA research.  This paper by Kim et al describes an algorithm for acutely identifying RA patients in large insurance claims.