 |
| JoAnn E. Manson, MD, DrPH, MACP |
JoAnn E. Manson, MD, DrPH, MACP, chief of the Division of Preventive Medicine, achieved 25 years of continuous funding from the National Heart, Lung and Blood Institute (NHLBI) with her recent R01 grant renewal for the cardiovascular disease (CVD) component of the Nurses’ Health Study. Manson has been the principal investigator (PI) of the CVD project, known as “CVD Risk Factors in Women” since 1998. The grant renewal also earned a perfect impact score of 10 (first percentile) on its review at an NHLBI study section.
The recent grant renewal supports Manson’s and her colleagues’ work, in collaboration with Lu Qi, MD, PhD, of Tulane University as co-PI, to conduct profiling of proteins and their cellular activities (proteomic profiling) and assess changes in these profiles over 10 years as predictors of coronary heart disease (CHD). The study also assesses proteomic profiles of circadian/temporal eating patterns and their relationship with incident CHD.
Manson is the chief of the Division of Preventive Medicine at the Brigham, professor of Medicine and the Michael and Lee Bell Professor of Women’s Health at Harvard Medical School, professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, and scientific advisor to the Brigham’s Mary Horrigan Connors Center for Women’s Health and Gender Biology. Her research interests include randomized clinical prevention trials of nutritional and lifestyle factors related to heart disease, diabetes and cancer, the role of endogenous and exogenous estrogens as determinants of chronic disease, life course-related risk factors for CVD in women, and biomarker predictors of CVD.
The NHLBI, part of the National Institutes of Health (NIH), provides training and education programs to promote the prevention and treatment of heart, lung and blood diseases to enhance the health of all individuals.
