Comprehensive Sickle Cell Disease Center

Each person with sickle cell disease is an individual. At the Brigham and Women’s Sickle Cell Disease Center we offer comprehensive care to meet individual needs. Whether a person is seen during a routine, scheduled appointment or during an acute episode, our clinicians provide care in the hospital and in the clinics to treat the entire person, providing personalized continuity of care.

Not only do we provide our patients with comprehensive medical care, but we also provide the resources to help with managing the disease day-to-day. A team of experienced physicians, nurse practitioners, nurses, social workers, and administrative staff are dedicated to the care of each patient in living a full active life.

We pride ourselves on being at the forefront of research, clinical trials, and medical advances in the care of individuals with sickle cell disease. We offer all FDA-approved treatments and are excited about soon being able to offer gene therapy to our patients.

Comprehensives Services

Our services include but are not limited to the following:

Outpatient Clinic

Our clinic is located at The Yawkey Building at the Dana-Farber Cancer Center. Our patients with sickle cell disease are seen in the clinic for health maintenance, prevention of complications, and for management of chronic complications of sickle cell disease, if they develop. Dr. Maureen Achebe and Elyse Mandell, NP see our patients in the clinic at Dana Farber. Experienced nurses provide treatment to our patients at the same location as the clinic.

Hematology Services
Dana-Farber Cancer Institute
450 Brookline Avenue
Brookline, MA 02215

Our Day Hospital

Our Day hospital is located at the Dana-Farber Cancer Institute. We offer urgent, same-day infusion appointments for hydration, pain management and transfusions, in a comfortable environment with caring nurses who understand sickle cell disease.

In-patient Hospital Facilities

Our patients are admitted to the in-patient hematology service on medical floors of Brigham and Women’s Hospital for management of acute complications of sickle cell disease. Elyse Mandell, NP our dedicated nurse practitioner with over 25 years of experience, working with our hematologists, hematology fellow and medical residents, provides continuity of care for the inpatient hematology service.

Community Outreach

Our patients seeking community involvement and support are referred to the Massachusetts Sickle Cell Association (MSCA), a community organization with whom we work. Dr. Achebe serves as the Vice Chair of the MSCA Board.

Maureen Achebe, MD, MPH and Elyse Mandell, NP, MSN treating a patient
Dr. Maureen Achebe, MD, MPH and nurse practitioner Elyse Mandell, NP, MSN treating a patient at our comprehensive clinic.

Our Treatment Team


Nurse Practitioners

  • Elyse Mandell, MSN, RNCS, Nursing Director

Social Workers

  • Kristy Katsetos, LICSW

Scheduling an Appointment

New patients who wish to make an appointment should call 1-617-732-6089. Patients who have already visited our clinic should call 1-617-732-5048 to make an appointment.

Clinical Affiliations

Our patients are routinely referred for specialty care to the following clinics:

Brigham and Women's Hospital Sickle Cell Information Resource Center

Sickle cell disease is an inherited red blood cell disorder. When a person is affected by sickle cell disease, their red blood cells contain a type of hemoglobin that does not carry oxygen effectively. Affected red blood cells are sickle shaped, hard, and sticky and do not pass through blood vessels well. Due to this, sickle cell disease generally causes pain episodes, low red blood cell count, anemia, and organ damage.

For more information on sickle cell disease, please explore the below resources:

If I have sickle cell trait, will my children have sickle cell disease? Do people with sickle cell disease live past childhood? Does sickle cell disease only affect Black people? Maureen Okam Achebe, M.D., Hematologist and Clinical Director for Hematology at Brigham and Women's Hospital and Assistant Professor at Harvard Medical School, clears up some common misconceptions about sickle cell disease.

What is sickle cell disease? Who does it affect? What causes it? Maureen Okam Achebe, M.D., Hematologist and Clinical Director for Hematology at Brigham and Women's Hospital and Assistant Professor at Harvard Medical School, explains how sickle cell disease is diagnosed and how it affects someone's daily life.

Learn more about Brigham and Women's Hospital

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