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Rehabilitation Services Research

Brigham and Women's Hospital (BWH) is engaged in rehabilitation research on clinical outcomes involving physical, occupational, and speech therapy. The aim of our clinical rehabilitation research is to investigate innovative treatment approaches and translate these findings into improved outcomes and quality of life for our patients.

Research Committee Publications Research Awards

2020 BWH Rehabilitation Research Paper Award

Tolland J, Miccile LA, Burke K. Effect of Physical Therapy Dosage on Functional Recovery Following TBI, Journal of Acute Care Physical Therapy: July 2019 - Volume 11 - Issue 3 - p 139-150 doi: 10.1097/JAT.0000000000000127

2019 BWH Rehabilitation Research Paper Awards

Perry, B., Richburg, B., Pomahac, B., Bueno, E., Green, J. The Effects of Lip-Closure Exercise on Lip Strength and Function Following Full Facial Transplantation: A Case Report. American Journal of Speech-Language Pathology, June 2017; 26 (2S), 682-686.

Rydingsward JE, Horkan CM, Mogensen KM, Quraishi SA, Amrein K, Christopher KB. (2016) Functional Status in ICU Survivors and Out of Hospital Outcomes: A Cohort Study. Crit Care Med. May 2016; 44(5):869-879.

Current Research Projects

Safran-Norton, CE, Neal, A, Wasan, AJ (PI), Edwards, R (co-investigator). Multi-center RCT to Determine Most Effective Interventions (Anti-Depressants and/or Enhanced Fear Avoidance Rehabilitation) for Patients with Chronic Low Back Pain and Negative Affect.

Safran-Norton, CE, Wagner, A (PI) and colleagues DFCI. A Multi-center Phase 1-2, Open-Label Study of DCC-3014 to assess the safety, Efficacy, Pharmakinetics and Pharmadynamics in patients with Advanced Tumors and Tenosynovial Giant Cell Tumor, October 2020-present

Primary Investigator- Henrikas Vaitkevicius MD. Contributors Tolland, Joseph PT, Iracheta, Christine. Evaluation of Analgesia and Sedation Management in Mechanically Ventilated Patients Admitted to the Neuroscience Intensive Care Unit.

Primary Investigator- Amato Anthony MD. Current contributors Flynn, Tricia PT, Russo, Emily PT, Miccile Lauren PT, Phase 2/3 study of Arimoclomol of Inclusion Body Myositis (IBM). A Randomized double-blinded Placebo-controlled Study.

Primary Investigator- Amato Anthony MD. Current contributors Flynn Tricia PT, Miccile Lauren PT, Russo, Emily PT. A Randomized, Double-Blind, Placebo-Controlled, Multi-center study to evaluate the Efficacy of ManNAc in subjects with GNE Myopathy.

Primary Investigator- Carty Matthew MD. Welch Sarah PT (Co-investigator). A Novel Approach to Lower Extremity Residual Limb Revision to Augment Volitional Motor Control, Restore Proprioception and Reverse Limb Atrophy. Sponsor Name- U.S. Army Medical Research Acquisition Activity

Primary Investigator- Carty Matthew MD. Welch Sarah PT (Co-investigator). Somatotropic Configuration of Distal Residual Limb Tissues in Lower Extremity Amputations. Sponsor Name- U.S. Army Medical Research Acquisition Activity, SUNDRY

Primary Investigator- Martin Scott MD. Contributors Safran-Norton Clare PT, Small Kristin MD, Rogers Dawn PT, Boehme Marty, PT, Breen Jillian, PT. Arthroscopic Labral Repair versus Physical Therapy for Tears of the Acetabular Labrum in Patients Age 40 and Older.

Primary Investigator- Katz Jeffrey MD. Contributors Safran-Norton Clare PT, Dechaves Leigh PT, Kale Madhuri PT, Sople Derek PT, Neal Jeffrey PT, Lizotte Marissa PT. Multicenter Randomized Control Trial: Treatment of Meniscal Problems in Osteoarthritis (TeMPO).

Primary Investigator Lozano-Calderon Santiago; Carty Matthew MD (site responsible investigator); Welch Sara PT (Co-investigator). Osseointegration Surgical Quality Registry

Primary Investigator Lozano-Calderon Santiago; Carty Matthew MD (site responsible investigator); Welch Sara PT (Co-investigator). OPRA Osseointegration HDE Use

Primary Investigator- Carty Matthew MD. Welch Sara PT (Co-investigator). An Osseointegrated Transfemoral Prosthesis Offering Long-Term Bi-Directional Efferent-Afferent Neural Transmission. Sponsor- MIT, DARPA

Co investigators: Taglieri-Noble Katie PT, Tolland Joseph PT Analysis of Physical Therapy Recommendations and Patient Follow up From a Multidisciplinary Parkinsons Disease clinic

Primary Investigator- Martin Scott MD. Contributors Safran-Norton Clare PT, Small Kristin MD, Rogers Dawn PT, Boehme Marty, PT, Breen Jillian, PT. Arthroscopic Labral Repair versus Physical Therapy for Tears of the Acetabular Labrum in Patients Age 40 and Older.

Primary Investigator- Katz Jeffrey MD. Contributors Safran-Norton Clare PT, Dechaves Leigh PT, Kale Madhuri PT, Sople Derek PT, Neal Jeffrey PT, Lizotte Marissa PT. Multicenter Randomized Control Trial: Treatment of Meniscal Problems in Osteoarthritis (TeMPO).

Rydingsward Jessica PT, Stuebe Jenna, PT, Tagerman, Michelle, PT. Cardiac Rehabilitation Preoperative Rehabilitation Project.

Primary Investigator- Carty Matthew MD. Contributors Welch Sara PT. Lower Extremity Amputee Research.

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