Rehabilitation Services Research

Brigham and Women’s Hospital (BWH) is engaged in rehabilitation research on clinical outcomes involving physical, occupational, and speech therapy. The aim of our clinical rehabilitation research is to investigate innovative treatment approaches and translate these findings into improved outcomes and quality of life for our patients.

Current Research Projects with the following content:

Primary Investigator- Henrikas Vaitkevicius MD. Contributors Tolland Joseph PT, Iracheta Christine. Evaluation of Analgesia and Sedation Management in Mechanically Ventilated Patients Admitted to the Neuroscience Intensive Care Unit.

Primary Investigator- Amato Anthony MD.  Current contributors Tolland Joseph PT, Flynn Tricia PT, Miccile Lauren PT, Mihalopoulous Mary PT. Past contributors Chused Samatha PT, Rydingsward Jessica PT.  Charcot-Marie-Tooth Disease type 1A. Phase 2/3 study of Arimoclomol of Inclusion Body Myositis.

Primary Investigator- Amato Anthony MD.  Current contributors Tolland Joseph PT, Flynn Tricia PT, Miccile Lauren PT, Mihalopoulous Mary PT. Past contributors Chused Samatha PT, Rydingsward Jessica PT.  International, multi-center, randomized, double-blind, placebo-controlled phase III study assessing in parallel groups the efficacy and safety of 2 doses of PXT3003 in patients with Charcot-Marie- Tooth Disease type 1A treated 15 months.

Primary Investigator- Amato Anthony MD.  Current contributors Tolland Joseph PT, Flynn Tricia PT, Miccile Lauren PT, Mihalopoulous Mary PT. Past contributors Chused Samatha PT, Rydingsward Jessica PT.  A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial of IMO-8400 in Patients with Dermatomyositis.

Primary Investigator- Tolland Joseph PT. Effects of early physical therapy intervention for the intensive care unit patient with neurologic injury at risk for developing ankle plantarflexion contracture: A retrospective chart review. 

Primary Investigator-Tolland Joseph PT.  Spontaneous Recovery in Young Traumatic Brain Injury Patient with Prolonged Acute Hospital Stay: A Case Study.

Primary Investigator- Mossanen Matthew MD. Contributors Kale Madhuri PT, and Cunningham Kristen, PT.  Comprehensive Patient-Centered Prehabilitation for Cystectomy.

Primary Investigator- Parnes Aric MD. Contributors Safran-Norton Clare PT.  A Randomized, Multicenter, open-label, Phase III Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab versus no Prophylaxis in Hemophilia A patients.

Primary Investigator- Safran-Norton Clare PT. Contributors Rogers Dawn PT, Martin Scott MD.  Physical Therapy Intervention for Patients with Hip Pain with or without Labral Surgery: Retrospective Review.

Primary Investigator- Martin Scott MD. Contributors Safran-Norton Clare PT, Small Kristin MD, Rogers Dawn PT, Boehme Marty, PT, Breen Jillian, PT.  Arthroscopic Labral Repair versus Physical Therapy for Tears of the Acetabular Labrum in Patients Age 40 and Older. 

Primary Investigator- Katz Jeffrey MD.  Contributors Safran-Norton Clare PT, Dechaves Leigh PT, Kale Madhuri PT, Sople Derek PT, Neal Jeffrey PT, Lizotte Marissa PT.  Multicenter Randomized Control Trial: Treatment of Meniscal Problems in Osteoarthritis (TeMPO). 

Rydingsward Jessica PT, Stuebe Jenna, PT, Tagerman, Michelle, PT. Cardiac Rehabilitation Preoperative Rehabilitation Project.

Primary Investigator- Carty Matthew MD.  Contributors Welch Sara PT.  Lower Extremity Amputee Research. 

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