Research at the Christou Lab is driven by our desire to improve the quality of life of ill infants, premature and full term. Babies are born with enormous potential but complications of transition to life outside the womb can compromise them for the rest of their lives. Our goal is to help every baby reach his or her full capacity to grow and develop normally. It is our view that clinical neonatologists caring for infants in the Neonatal Intensive Care Unit (NICU) have a unique perspective, and the opportunity and obligation to push the envelope in research and clinical innovation. We bring clinically relevant questions from the NICU to the research laboratory and innovative interventions from the laboratory to the NICU. Our research efforts are focused on Bronchopulmonary Dysplasia, the most common long term complication of premature birth and Pulmonary Hypertension, a disease of full term and premature infants, children and adults. Using preclinical models and translational approaches, we seek to understand the factors contributing to these diseases and develop novel ways to treat them.