Cognitive Aging Lab Publications

Feng NC, Ryan E, Kidane M, Tusch ES, McFeeley BM, Carlsson R, Mohammed AH, Hakansson K, Daffner KR. Feasibility of an at-home, web-based, interactive exercise program for older adults. Alzheimer’s and Dementia: Translational Research & Clinical Interventions. 2019; 5:825-833.

Behforuzi H, Feng NC, Billig AR, Ryan E, Tusch ES, Holcomb P, Mohammed AH, Daffner KR. Markers of Novelty Processing in Older Adults Are Stable and Reliable. Frontiers in Aging Neuroscience. 2019; 11:165.

Tusch ES, Feng NC, Holcomb PJ, Daffner KR. Task-irrelevant novel sounds have antithetical effects on visual target processing young and old adults. Frontiers in Aging Neuroscience. 2017; 9:348.

Tusch ES, Alperin BR, Ryan E, Holcomb PJ, Mohammed AH, Daffner KR. Changes in neural activity underlying working memory after computerized cognitive training in older adults. Frontiers in Aging Neuroscience. 2016; 8:255.

Tusch ES, Alperin BR, Holcomb PJ, Daffner KR. Increased early processing of task-irrelevant auditory stimuli in older adults. PloS One. 2016; 11:11. Epub 2016/11/03.

Simon SS, Tusch ES, Holcomb PJ, Daffner KR. Increasing Working Memory Load Reduces Processing of Cross-Modal Task-Irrelevant Stimuli Even after Controlling for Task Difficulty and Eecutive Capacity. Frontiers in Human Neuroscience. 2016; 10:380.

Porto FHG, Tusch ES, Fox AM, Alperin B, Holcomb PJ, Daffner KR. One of the most well-established age-related changes in neural activity disappears after controlling for visual acuity. NeuroImage, 130, 115-122. E-pub 2016/01/31

Alperin BR, Tusch ES, Mott KK, Holcomb PJ, Daffner KR. Investigating age-related changes in anterior and posterior neural activity throughout the information processing stream. Brain and Cognition, 2015; 99, 118-127

Porto, FH, Fox, AM, Tusch ES, Sorond F, Mohammed AH, & Daffner KR. In vivo evidence for neuroplasticity in older adults. Brain Research Bulletin, 2015; 114, 56-61.

Mott KK, Alperin BR, Fox AM, Holcomb PJ, Daffner KR. The impact of executive capacity and age on mechanisms underlying multidimensional feature selection. Neuropsychologia, 2015; 70C: 30-42.

Daffner KR, Alperin BR, Mott KK, Tusch E, Holcomb PJ. Age-related differences in early novelty processing: Using PCA to parse the overlapping anterior P2 and N2 components. Biological Psychology, 2015; 105:83-94.

Mott KK, Alperin BR, Holcomb PJ, Daffner KR. Age-related decline in differentiated neural responses to rare target versus frequent standard stimuli. Brain Research, 2014; 1587, 97-111.

Alperin BR, Mott KK, Holcomb PJ, Daffner KR. Does the age-related “anterior shift” of the P3 reflect an inability to habituate the novelty response? Neuroscience Letters, 2014; 557, 6-10

Zhuravleva, TY, Alperin BR, Haring AE, Rentz DM, Holcomb PJ, Daffner KR. Age-related decline in bottom-up processing and selective attention in the very old. Journal of Clinical Neurophysiology, 2014; 31(3), 261-271.

Alperin B, Mott K, Rentz D, Holcomb P, Daffner, KR. Investigating the age-related “anterior shift” in the scalp distribution of the P3b component using principal component analysis. Psychophysiology, 2014; 51(7), 620-633.

Daffner KR, Alperin B, Mott K, Holcomb P. Age-related differences in the automatic processing of single letters: implications for selective attention. NeuroReport, 2014; 25(2), 77-82.

Alperin B, Haring A, Zhuravleva T, Holcomb P, Rentz D, Daffner KR. The dissociation between early and late selection in older adults. Journal of Cognitive Neuroscience, 2013; 25(12), 2189-2206.

Haring AE, Zhuravleva TY, Alperin BR, Rentz DM, Holcomb PJ, Daffner KR. Age-related differences in enhancement and suppression of neural activity underlying selective. Brain Research, 2013; 1499: 69-79.

Daffner KR, Haring A, Alperin B, Zhuravleva T, Mott K, Holcomb P. The impact of visual acuity on age-related differences in neural markers of early visual processing. NeuroImage, 2012; 67, 127-136.

Daffner KR, Chong H, Sun X, Tarbi EC, Riis JL, McGinnis SM, Holcomb PJ. Mechanisms underlying age and performance related differences in working memory. Journal of Cognitive Neuroscience, 2011; 23: 1298-1314.

Daffner KR, Sun X, Tarbi EC, Rentz DM, Holcomb PJ, Riis JL. Does compensatory neural activity survive old-old age? NeuroImage, 2011; 54: 427-438

Tarbi EC, Sun X, Holcomb PJ, Daffner KR. Surprise? Early visual novelty processing it not modulated by attention. Psychophysiology, 2011; 48: 624-632.

Chemali Z, Withall A, Daffner KR. The plight of caring for young patients with frontotemporal dementia. American Journal of Alzheimer’s Disease and Other Dementias, 2010; 25: 109-115.

Daffner KR (medical editor). Improving Memory: Understanding Age-Related Memory Loss. Boston, Harvard Health Publications, 2010.

Daffner KR. Promoting Successful Cognitive Aging: A Comprehensive Review. Journal of Alzheimer’s Disease, 2010; 19: 1101-1122.

Wolk DA, Sen NM, Chong H, Riis JL, McGinnis SM, Holcomb PJ, Daffner KR. ERP correlates of item recognition memory: Effects of age and performance. Brain Research, 2009; 1250: 218-231.

Chong H, Riis JL, Scott SM, Williams DM, Holcomb PJ, Daffner KR. To Ignore or Explore: Top Down Modulation of Novelty Processing. Journal of Cognitive Neuroscience, 2008; 20: 120-134.

Daffner KR, Searl, MM. The dysexecutive syndromes. In: Goldenberg G, Miller B, , eds., Handbook of Clinical Neurology: Neuropsychology and Behavioral Neurology. New York, Elsevier Press, 2008.

Daffner KR, Sherman JC, Gonzalez RG, Hasserjian RP. A 65-year-old man with confusion and memory loss. Case Records of the Massachusetts General Hospital. New England Journal of Medicine, 2008; 359: 2155-64.

Riis JL, Chong H, Ryan KK, Wolk DA, Rentz DM, Holcomb PJ, Daffner KR. Compensatory neural activity distinguishes different patterns of normal cognitive aging. NeuroImage, 2008; 39: 441-454.

Riis JL, Chong H, Ryan KK, Wolk DA, Rentz DM, Holcomb PJ, Daffner KR. Compensatory neural activity distinguishes different patterns of normal cognitive aging. NeuroImage, 2008; 39: 441-454.

Cognitive Neuroscience Society; Annual Meeting Program 2007; A supplement of the Journal of Cognitive Neuroscience.

Daffner KR, Chong H, Riis J, Rentz DM, Wolk DA. Cognitive status impacts age-related changes in attention to novel and target events in normal adults. Neuropsychology 2007; 21: 291-300.

Scharf JM, Daffner KR. NSAIDs in the prevention of dementia: A Cache-22, Neurology 2007; 69: 235-236.

Rentz DM, Huh TJ, Sardinha LM, Moran EK, Becker JA, Daffner KR, Sperling RA, Johnson KA. Intelligence quotient-adjusted memory impairment is associated with abnormal SPECT perfusion. Journal of the International Neuropsychological Society 2007; 13: 821-831.

Wolk DA, Schacter DL, Lygizos M, Sen NM, Chong H, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of remember/know decisions: Association with the late posterior negativity. Biological Psychology 2007; 75: 131-135.

Daffner KR, Ryan KK, Williams DM, Budson AE, Rentz DM, Wolk DA, Holcomb PJ. Age-related differences in attention to novelty among cognitively high performing adults. Biological Psychology 2006; 72: 67-77.

Daffner KR, Ryan KK, Williams DM, Budson AE, Rentz DM, Wolk DA, Holcomb PJ. Increased Responsiveness to Novelty is Associated with Successful Cognitive Aging. Journal of Cognitive Neuroscience 2006; 18: 1759-1773.

Wolk DA, Schacter DL, Lygizos M, Sen NM, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of recognition memory: Effects of retention interval and false alarms. Brain Research 2006; 1096: 148-162.

Budson AE, Dodson CS, Daffner KR, Schacter DL. Metacognition and false recognition in Alzheimer’s disease: Further exploration of the distinctiveness heuristic. Neuropsychology 2005; 19: 253-258.

Budson AE, Droller DBJ, Dodson CS, Schacter DL, Rugg MD, Holcomb PJ, Daffner, KR. Electrophysiological dissociation of picture versus word encoding: The distinctiveness heuristic as a retrieval orientation. Journal of Cognitive Neuroscience 2005; 17: 1181-1193.

Daffner KR, Ryan KK, Williams DM, Budson AE, Rentz DM, Scinto LFM, Holcomb PJ. Age-sensitivity of the P3 in cognitively high performing adults: Unsettled issues. Neurobiology of Aging 2005; 26: 1301-1304.

Daffner KR, Ryan KK, Williams DM, Budson AE, Rentz DM, Scinto LFM, Holcomb PJ. Age-related differences in novelty and target processing among cognitively high performing adults. Neurobiology of Aging 2005; 26: 1283-1295.

Wolk DA, Schacter DL, Berman AR, Holcomb PJ, Daffner KR, Budson AE. Patients with mild Alzheimer’s disease attribute conceptual fluency to prior experience. Neuropsychologia 2005; 43: 1162-1172.

Rentz DM, Huh TJ, Faust RR, Budson AE, Scinto LFM, Sperling RA, Daffner KR. Use of IQ-adjusted norms to predict progressive cognitive decline in highly intelligent elders. Neuropsychology 2004; 18: 38-49.

Wolk DA, Schacter DL, Berman AR, Holcomb PJ, Daffner KR, Budson AE. An electrophysiological investigation of the relationship between conceptual fluency and familiarity. Neuroscience Letters, 2004; 369: 150-155.

Daffner KR, Scinto LFM, Weitzman AM, Faust R, Rentz DM, Budson AE, Holcomb PJ. Frontal and parietal components of a cerebral network mediating voluntary attention to novel events. Journal of Cognitive Neuroscience 2003; 15: 294-313.

Daffner KR, Rentz D, Scinto LFM, Faust R, Budson AE, Holcomb P. Pathophysiology underlying diminished attention to novel events in patients with early AD. Neurology 2001; 56: 1377-1383.

Daffner KR, Mesulam MM, Calvo V, Faust R, Scinto LFM, Holcomb P. An Electrophysiological Index of Stimulus Unfamiliarity. Psychophysiology 2000, 37: 737-747.

Daffner KR, Mesulam MM, Scinto LFM, Acar D, Calvo V, Faust R, Chabrerie A, Kennedy B, Holcomb P. The central role of the prefrontal cortex in directing attention to novel events. Brain 2000, 123: 927-939.

Daffner KR, Mesulam MM, Scinto LFM, Calvo V, West WC, Holcomb P. The influence of stimulus deviance on electrophysiologic and behavioral responses to novel events. Journal of Cognitive Neuroscience 2000, 12: 393-406.

Daffner KR, Scinto L. Chapter 1: An Introduction. Early Diagnosis of Alzheimer's Disease. Totowa, Humana Press, 2000.

Scinto LFM and Daffner KR (editors). Early Diagnosis of Alzheimer's Disease. Totowa, Humana Press, 2000.

Daffner KR, Mesulam MM, Cohen L, Scinto, LFM. Mechanisms underlying diminished novelty-seeking behavior in patients with probable Alzheimer’s disease. Neuropsychiatry, Neuropsychology, and Behavioral Neurology 1999; 12: 58-66.

Daffner KR, Ahern GL, Weintraub S, Mesulam MM. Dissociated neglect behavior following sequential strokes in the right hemisphere. Annals of Neurology l990; 28: 97-101.