Center for Reconstructive and Restorative Surgery Research

The history of transplant surgery is rooted in plastic and reconstructive surgery. In the great tradition of plastic surgeon and early transplant pioneer Dr. Joseph Murray, the Center for Reconstructive and Restorative Surgery Research at Brigham and Women’s is focused on improving the outcomes of reconstructive surgery and increasing knowledge in all areas of vascularized composite allotransplantation (VCA).

Transplantation allows for restoration of form and function of an organ with associated need for immune suppression to prevent rejection.  New applications in reconstructive surgery revolutionized our treatment options for the most severe body defects.  Replacement of missing parts with identical ones has transformed reconstructive to restorative surgery with unprecedented treatment options for our patients.

Our major research interests are focused on transplantation of tissues, prevention of rejection, and isolated limb perfusion.