BWH Pituitary Program Research Publications

  • Jagannathan J, Sheehan JP, Pouratian N, Laws ER Jr, Steiner L, Vance ML. Gamma Knife radiosurgery for acromegaly: outcomes after failed transsphenoidal surgery. Neurosurgery. 2008;62(6):1262-9.
  • Prevedello DM, Pouratian N, Sherman J, Jane JA Jr, Vance ML, Lopes MB, Laws ER Jr. Management of Cushing’s disease: outcome in patients with microadenoma detected on pituitary magnetic resonance imaging. J Neurosurg. 2008;109(4):751-9.
  • Patil CG, Prevedello DM, Lad SP, Vance ML, Thorner MO, Katznelson L, Laws ER Jr. Late recurrences of Cushing’s disease after initial successful transsphenoidal surgery. J Clin Endocrinol Metab. 2008; 93(2):358-62.
  • Semple PL, Jane JA Jr, Lopes MB, Laws ER. Pituitary apoplexy: correlation between magnetic resonance imaging and histopathological results. J Neurosurg. 2008;108(5):909-15.
  • Sherman JH, Pouratian N, Okonkwo DO, Jane JA Jr, Laws ER. Reconstruction of the sellar dura in transsphenoidal surgery using an expanded polytetrafluoroethylene dural substitute. Surg Neurol. 2008;69(1):73-6.
  • Zada, G., et al., The neurosurgical anatomy of the sphenoid sinus and sellar floor in endoscopic transsphenoidal surgery. J Neurosurg.114(5): p. 1319-30.
  • Laws ER. Surgery for acromegaly: evolution of the technques and outcomes. Rev Endocr Metab Disord. 2008;9(1):67-70.
  • Gosvenor A, Laws ER. The evolution of extracranial approaches to the pituitary and anterior skull base. Pituitary. 2008;11(4):337-45.
  • Zada, G., et al., Transsphenoidal surgery in patients with acromegaly: operative strategies for overcoming technically challenging anatomical variations. Neurosurg Focus. 29(4): p. E8.
  • Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region. Neurosurg Rev. 2008;31(1):55-64.
  • Prevedello DM, Pouratian N, Sherman J, Jane JA Jr, Vance ML, Lopes MB, Laws ER Jr. Management of Cushing’s disease: outcome in patients with microadenoma detected on pituitary magnetic resonance imaging. J Neurosurg. 2008;109(4):751-9.
  • Laws ER. Endoscopic surgery for cystic lesions of the pituitary region. Nat Clin Pract Endocrinol Metab. 2008;4(12):662-3.
  • Pires de Aguiar PH, Laws ER Jr, Dodd R, Hwang P, Getz AE. Endoscopic endonasal approach to pituitary adenomas. J Bras Neurocirurg. 2008;19(2):54-63.
  • Jagannathan J, Kanter AS, Olson C, Sherman JH, Laws ER Jr, Sheehan JP. Applications of radiotherapy and radiosurgery in the management of pediatric Cushing’s disease: a review of the literature and our experience. J Neurooncol. 2008;90(1):117-24.
  • Zada, G., R. Du, and E.R. Laws, Jr., Defining the "edge of the envelope": patient selection in treating complex sellar-based neoplasms via transsphenoidal versus open craniotomy. J Neurosurg. 2011: 114(2): p. 286-300.
  • Cappabianca P, Kelly DF, Laws ER Jr. Endoscopic transnasal versus open transcranial cranial base surgery: the need for a serene assessment. Neurosurgery. 2008;63(4 Suppl 2):240-1.
  • Patil CG, Veeravagu A, Prevedello DM, Katznelson L, Vance ML, Laws ER Jr. Outcomes after repeat transsphenoidal surgery for recurrent Cushing’s disease. Neurosurgery. 2008;63(2):266-70.
  • Kaptain GJ, Vincent DA, Sheehan JP, Laws ER Jr. Transsphenoidal approaches for the extracapsular resection of midline suprasellar and anterior cranial base lesions. Neurosurgery. 2008;62(6 Suppl 3):1264-71.
  • Jagannathan J, Yen CP, Pouratian N, Laws ER, Sheehan JP. Stereotactic radiosurgery for pituitary adenomas: a comprehensive review of indications, techniques and long-term results using the Gamma Knife. J Neurooncol. 2009;92(3):345-56.
  • Melmed S, Colao A, Barkan A, Molitch M, Grossman AB, Kleinberg D, Clemmons D, Chanson P, Laws E, Schlechte J, Vance ML, Ho K, Giustina A; Acromegaly Consensus Group. Guidelines for acromegaly management: an update. J Clin Endocrinol Metab. 2009;94(5):1509-17.
  • Smith PW, Turza KC, Carter CO, Vance ML, Laws ER, Hanks JB. Bilateral adrenalectomy for refractory Cushing disease: a safe and definitive therapy. J Am Coll Surg. 2009;208(6):1059-64.
  • Zada, G., et al., Atypical pituitary adenomas: incidence, clinical characteristics, and implications. J Neurosurg. 114(2): p. 336-44.
  • Isolan GR, de Aguiar PH, Laws ER, Strapasson AC, Piltcher O. The implications of microsurgical anatomy for surgical approaches to the sellar region. Pituitary. 2009;12(4):360-7.
  • Davis G, Marion DW, George B, Le Roux P, Laws ER, McCrory P. Clinics in neurology and neurosurgery of sport: mass lesions. Benign brain tumours. Br J Sports Med. 2009;43(8):619-22.
  • Jagannathan J, Yen CP, Pouratian N, Laws ER, Sheehan JP. Stereotactic radiosurgery for pituitary adenomas: a comprehensive review of indications, techniques and long-term results using the Gamma Knife. J Neurooncol. 2009;92(3):345-56.
  • Sheehan JP, Williams B, Laws ER. Current concepts in stereotactic radiosurgery for pituitary adenomas. World Neurosurgery. 2009;7(1).
  • Jane JA Jr., Laws ER Jr. Endoscopy versus MR imaging. J Neurosurg. 2010;112(4):734.
  • Ray DK, Yen CP, Vance ML, Laws ER, Lopes B, Sheehan JP. Gamma knife surgery for lymphocytic hypophysitis. J Neurosurg. 2010;112(1):118-21.
  • Agarwalla PK, Dunn GP, Laws ER. An historical context of modern principles in the management of intracranial injury from projectiles.Neurosurg Focus. 2010;28(5):E23.
  • Jane JA Jr., Kiehna E, Payne SC, Early SV, Laws ER Jr. Early outcomes of endoscopic transsphenoidal surgery for adult craniopharyngiomas. Neurosurg Focus. 2010;29(4):E9.
  • Zada, G., et al., Midline filum of the sellar dura: a useful landmark during endoscopic transsphenoidal pituitary surgery. Neurosurgery.67(2 Suppl Operative): p. 391-4.
  • Igreja S, Chahal HS, King P, Bolger GB, Srirangalingam U, Guasti L, Chapple JP, Trivellin G, Gueorguiev M, Guegan K, Stals K, Khoo B, Kumar AV, Ellard S, Grossman AB, Korbonits M; International FIPA Consortium. Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families. Hum Mut. 2010;31(8):950-60.
  • Bush ZM, Longtine JA, Cunningham T, Schiff D, Jane JA Jr, Vance ML, Thorner MO, Laws ER Jr, Lopes MB. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab. 2010;95(11):E280-90.
  • Hamnvik OP, Laury AR, Laws ER Jr, Kaiser UB. Lymphocytic hypophysitis with diabetes insipidus in a young man. Nat Rev Endocrinol. 2010;6(8):464-70.
  • Jane JA Jr, Prevedello DM, Alden TD, Laws ER Jr. The transspehoidal resection of pediatric craniopharyngiomas: a case series. J Neurosurg Pediatr. 2010;5(1):49-60.
  • Laws ER Jr, Jane JA Jr. Craniopharyngioma. J Neurosurg Pediatr. 2010;5(1):27-8.
  • Jagannathan J, Bourne TD, Schlesinger D, Yen CP, Shaffrey ME, Laws ER Jr, Sheehan JP. Clinical and pathological characteristics of brain metastasis resected after failed radiosurgery.Neurosurgery. 2010;66(1):208-17.
  • Zada, G., et al., Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships. Neurosurg Focus. 28(4): p. E4.
  • Zada, G., et al., Cushing's disease and idiopathic intracranial hypertension: case report and review of underlying pathophysiological mechanisms. J Clin Endocrinol Metab. 95(11): p. 4850-4.
  • Bush ZM, Lopes MB, Hussaini IM, Jane JA Jr, Laws ER Jr, Vance ML. Immunohistochemistry of COUP-TFI: an adjuvant diagnostic tool for the identification of corticotroph microadenomas. Pituitary. 2010;13(1):1-7.
  • Laws ER Jr. Music and the brain. World Neurosurg. 2010;73(5):148.
  • Pendleton C, Adams H, Laws ER, Quinones-Hinojosa A. The elusive Minnie G.: revisting Cushing’s case XLV, and his early attempts at improving quality of life. Pituitary. 2010;13(4):361-6.
  • de Aguiar PH, Aires R, Laws ER, Isolan GR, Logullo A, Patil C, Katznelson L. Labeling index in pituitary adenomas evaluated by means of MIB-1: is there a prognostic role? A critical review.Neurol Res. 2010;32(10):1060-71.
  • Zada, G., N. Lin, and E.R. Laws, Jr., Patterns of extrasellar extension in growth hormone-secreting and nonfunctional pituitary macroadenomas. Neurosurg Focus. 29(4): p. E4.
  • Sheehan JP, Pouratian N, Steiner L, Laws ER, Vance ML. Gamma Knife surgery for pituitary adenomas: factors related to radiological and endocrine outcomes. J Neurosurg. 2011;114(2):303-9.
  • Kaptain GJ, Kanter AS, Hamilton DK, Laws ER. Management and implications of intraoperative cerebrospinal fluid leak in transnasoseptal transsphenoidal microsurgery. Neurosurgery. 2011;68(1 Suppl Operative):144-50.
  • Zada, G. and E.R. Laws, Surgical management of craniopharyngiomas in the pediatric population. Horm Res Paediatr.74(1): p. 62-6.
  • Gopalan R, Schlesinger D, Vance ML, Laws E, Sheehan J. Long-term outcomes after Gamma knife radiosurgery for patients with a nonfunctioning pituitary adenoma. Neurosurgery. 2011;69(2):284-93.
  • Nosé V, Ezzat S, Horvath E, Kovacs K, Laws ER, Lloyd R, Lopes MB, Asa SL. Protocol for the examination of specimens from patients with primary pituitary tumors. Arch Pathol Lab Med. 2011;135(5):640-6.
  • Zada, G. and E.R. Laws, Jr., Simultaneous transsphenoidal and intraventricular endoscopic approaches for macroadenomas with extensive suprasellar extension: surgery from below, above, or both?World Neurosurg. 74(1): p. 109-10.
  • Laws ER Jr. Surgical outcome in 90 patients with craniopharyngiomas: an evaluation of the transsphenoidal approach. World Neurosurg. 2010;74(2-3):254-5.
  • Sherman JH, Redpath GT, Redick JA, Purow BW, Laws ER, Jane JA Jr, Shaffrey ME, Hussaini IM. A novel fixative for immunofluorescence staining of CD133-positive glioblastoma stem cells. J Neurosci Methods. 2011;198(1):99-102.
  • Jane JA Jr, Starke RM, Elzoghby MA, Reames DL, Payne SC, Thorner MO, Marshall JC, Laws ER Jr, Vance ML. Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome. J Clin Endocrinol Metab. 2011 Jun 29.
  • Srinivasan L, Laws ER, Dodd RL, Monita MM, Tannenbaum CE, Kirkeby KM, Chu OS, Harsh Iv GR, Katznelson L. The dynamics of post-operative plasma ACTH values following transsphenoidal surgery for Cushing’s disease. Pituitary. 2011 Feb 6.
  • Zada, G., L.S. Governale, and E.R. Laws, Jr., Intraoperative conversion from endoscopic to microscopic approach for the management of sellar pathology: incidence and rationale in a contemporary series. World Neurosurg. 73(4): p. 334-7.
  • Iuliano S, Laws ER Jr. Management of pituitary tumors in pregnancy. Semin Neurol. 2011 Sep;31(4):423-8.
  • Iuliano, SL, Laws, ER. The diagnosis and management of lymphocytic hypophysitis. Expert Review of Endocrinology and Metabolism. 2011: 6: 777-783.
  • Aytug, S, Laws, ER, Vance, ML. Assessment of the utility of the high-dose dexamethasone suppression test in confirming the diagnosis of Cushing disease. Endocrine Practice. 2012. 18: 152-157
  • Barkhoudarian, G, Laws, ER. Craniopharyngioma: history. Pituitary. 2012: 15:1.
  • Puri, AS, Zada, G, Zarzour, H, Laws, ER, Frerichs, K. Cerebral vasospasm after transsphenoidal resection of pituitary macroadenomas: Report of 3 cases and review of literature. Operative Neurosurgery. 2012. 71: 173-180
  • Starke RM, Reames DL, Ching-Jen C, Laws ER, Jane JA. Endoscopic transsphenoidal surgery for Cushing disease: Techniques, outcomes, and predictors of remission. Neurosurgery. 2013: 72: 240-247.
  • Laws, ER. The Evolution of Cushing’s Surgical Treatment of Pituitary Lesions. World Neurosurgery. 2013: 79: 290-291.
  • Iuliano, S. & Laws, ER. Early recognition of cushing’s disease: a case study. Journal of the American Academy of Nurse Practitioners, 2013: 25 (8): 402-406.
  • Scangas, GA., Laws, ER. Pituitary Incidentalomas. Pituitary. 2013. [Epub]
  • Cho, CH, Barkhoudarian, G, Hsu, L., Bi, WL., Zamani, AA., Laws, ER. Magnetic Resonance imaging validation of pituitary gland compression and distortion by typical sellar pathology. J Neurosurgery. 2013 [Epub ahead of print]
  • Iuliano, SI., Laws, ER. Recognizing the clinical manifestations of acromegaly: Case Studies. Journal of American Association of Nurse Practitioners. 2013. [Epub ahead of print]
  • DiDivitiis, E., Laws, ER. The Transnasal versus transcranial approach to lesions of the anterior skull base. World Neurosurgery. 2013:80 (6) 728-729.
  • Laws ER, De Los Reyes K, Rincon-Torroella J, Lumbar Drains in transsphenoidal surgery. Neurosurgery. 2013: 118: 480-481.
  • Laws ER, Starke RM, Reames DL, Chen CJ, Jane JA. Endoscopic Transsphenoidal surgery for Cushing’s Disease: Techniques, Outcomes, and Predictors of Remission. Neurosurgery- Online. 2013 : 72: 420-427.
  • Hughes J, Barhoudarian G, Ciarlini P, Laws ER, Mody E, Inzucchi SE, Woodmansee WW. Refractory pituitary granulomatosis with polyangiitis (Wegener’s) treated with rituximab. Endocrine Practice. 2013: 19: 3, 117.
  • Laws, ER, Iuliano, S. Persistant Cushing’s disease after unsuccessful surgery, assessment and strategies. Cushing’s Support & Research Foundation Newsletter. Winter 2013.
  • Laws ER, Ezzat S, Asa, SL, Rio LM, Michael L, Knutzen R (eds.): Pituitary Disorders – Diagnosis and Management. Wiley-Blackwell; London, 357pp, 2013.

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