Molecular Diagnostic Laboratory

The Molecular Diagnostics Test Menu includes:

  • Quantitative RT-PCR (Taqman assay) for BCR-ABL1 mRNA
  • ABL1 kinase domain mutational analysis for Gleevec resistance in CML patients
  • Qualitative RT-PCR for PML-RARA mRNA
  • JAK2 V617 Fdetection for chronic myeloproliferative disorders
  • PCR analysis of immunoglobulin or T cell receptor genes for B or T cell clonality
  • KRAS mutation analysis as a predictive indicator for therapeutic response in metastatic colon cancer
  • BRAF mutation analysis for Thyroid papillary carcinoma, melanoma and colon cancer and low grade gliomas
  • EGFR mutation analysis as a predictive indicator for therapeutic response in metastatic non-small cell lung cancer
  • MGMT promoter methylation analysis as a prognostic and predictive indicator in glioblastoma
  • Microsatellite Instability (MSI) testing as a screen for Hereditary Non-polyposis Colorectal Carcinoma (HNPCC)
  • Cystic Fibrosis carrier screening test for 39 commonly mutated loci within the CFTR gene (Luminex Tag-IT assay)
  • Factor V Leiden and Prothrombin (F2 G20210A) point mutation (Invader assay)
  • HPV screening for high risk DNA types (Qiagen/Digene Hybrid Capture II)
  • HPV genotyping by restriction-length polymorphism analysis
  • Southern blot analysis of immunoglobulin or T cell receptor genes for B or T cell clonality and/or for clonal EBV

Requisition Forms

Fellowship Information

Information on the Molecular Genetics Fellowships can be found here.

Contact Information

For more information please contact 857-307-1500.

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